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Trichothecene Mycotoxins Mycology, Chemistry, and Toxicology

  • Yoshio Ueno

Abstract

The mycotoxins reviewed in this section comprise a family of closely related sesquiterpenoids produced by various species of fungi such as Fusarium, Myrothecium, Trichoderma, Trichothecium, Cephalosporium, Verticimonosporium and Stachybotrys,and are classified as trichothecenes after trichothecin, the first member of the group to be discovered (Freeman and Morrison, 1949). In the early stage of trichothecene studies, the first isolate, trichothecin, was discovered as a result of screening of antifungal metabolites in a culture of Trichothecium roseum. The following survey demonstrated that Myrothecium roridum and M. verrucaria produced potent antifungal metabolites, which were designated as verrucarins A through J and rondins A through E (Härri et al.,1962). Structural studies on these compounds demonstrated that they are macrocyclic trichothecenes (Böhner et al., 1965).

Keywords

Trichothecene Mycotoxin Toxic Principle Feed Refusal Macrocyclic Trichothecene Crude Toxin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer Science+Business Media New York 1980

Authors and Affiliations

  • Yoshio Ueno
    • 1
  1. 1.Department of Toxicology and Microbial Chemistry, Faculty of Pharmaceutical SciencesTokyo University of ScienceTokyoJapan

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