Abstract
The mechanoreceptive organelle of a hair cell, the hair bundle, consists primarily of a bevelled array of hexagonally packed stereocilia. When a mechanical stimulus is applied at a bundle’s tip, the individual stereocilia behave as rigid rods that bend at their basal insertions into the cell’s apical surface. The 20 or so actin filaments that form the cytoskeleton in this tapered basal region probably contribute much of the bundle’s steadystate stiffness, which is approximately 1 mN·m−1 for the hair cells of amphibians (Howard and Ashmore, 1986; Howard and Hudspeth, 1987a; Denk el al., 1989), reptiles (Crawford and Fettiplace, 1985), and mammals (Flock and Strelioff, 1984; Russell et al., 1989).
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© 1990 Springer-Verlag Berlin Heidelberg
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Jaramillo, F., Howard, J., Hudspeth, A.J. (1990). Calcium Ions Promote Rapid Mechanically Evoked Movements of Hair Bundles. In: Dallos, P., Geisler, C.D., Matthews, J.W., Ruggero, M.A., Steele, C.R. (eds) The Mechanics and Biophysics of Hearing. Lecture Notes in Biomathematics, vol 87. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-4341-8_4
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DOI: https://doi.org/10.1007/978-1-4757-4341-8_4
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