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Multiple New Isoforms of the Human Prolactin Receptor Gene

  • Josephine F. Trott
  • Russell C. Hovey
  • Sailaja Koduri
  • Barbara K. Vonderhaar
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 554)

Abstract

Prolactin (PRL) is a polypeptide hormone with a clear role in promoting mammary gland growth, differentiation, and lactogenesis. In addition, endocrine and/or autocrine/ paracrine PRL (Clevenger et al. 1995; Ginsburg & Vonderhaar 1995) promotes mammary carcinogenesis in rodents (Wennbo et al. 1997) and also may contribute to the initiation and progression of human breast cancer (Hankinson et al. 1999).

Keywords

Correspond Author Chloramphenicol Acetyl Transferase Prolactin Receptor Short Isoforms Dominant Negative 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2004

Authors and Affiliations

  • Josephine F. Trott
    • 1
  • Russell C. Hovey
    • 1
  • Sailaja Koduri
    • 2
  • Barbara K. Vonderhaar
    • 2
  1. 1.Lactation and Mammary Gland Biology Group, Department of Animal ScienceUniversity of VermontBurlingtonUSA
  2. 2.Molecular and Cellular Endocrinology Section, Mammary Biology and Tumorigenesis LaboratoryNational Cancer InstituteBethesdaUSA

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