Efforts to Prevent Mother-to-Child Transmission of Human Immunodeficiency Virus Type 1 through Human Milk

Past, Present, and Future
  • S. Urdaneta
  • C. M. Berlin
  • M. K. Howett
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 554)


About a third of mothers who are positive for human immunodeficiency virus (HIV) infect their newborn infants (UNAIDS/WHO 2002). Most vertical transmission occurs during gestation and delivery (Edgeworth & Ugen 2000). Breastfeeding by an HIV-positive woman adds an additional 14% to the risk of in utero and intrapartum transmission (Dunn et al. 1992). Alternatives to breastfeeding or modulation of breastfeeding techniques that are accessible, acceptable, and safe to use in low- and middle-income countries are in demand. Thus, research on making breastfeeding safer is a high priority. The purpose of this chapter is to review treatment approaches to decrease or eliminate HIV in human milk.


Human Immunodeficiency Virus Sodium Dodecyl Sulfate Human Immunodeficiency Virus Type Human Milk Human Immunodeficiency Virus Transmission 
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Copyright information

© Springer Science+Business Media New York 2004

Authors and Affiliations

  • S. Urdaneta
    • 1
  • C. M. Berlin
    • 2
    • 3
  • M. K. Howett
    • 1
    • 4
  1. 1.Departments of Microbiology and Immunology, College of Medicine, M.S. Hershey Medical CenterPennsylvania State UniversityHersheyUSA
  2. 2.Department of Pediatrics, College of MedicinePennsylvania State UniversityHersheyUSA
  3. 3.Department of Pharmacology, College of MedicinePennsylvania State UniversityHersheyUSA
  4. 4.Department of Obstetrics & Gynecology, College of MedicinePennsylvania State UniversityHersheyUSA

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