Assembling, Connecting, and Maintaining the Cochlear Nucleus

  • Edwin W. Rubel
  • Thomas N. Parks
  • Lance Zirpel
Part of the Springer Handbook of Auditory Research book series (SHAR, volume 23)


The cochlear nucleus (CN) is an essential synaptic intermediary in the ascending auditory pathway and the site of remarkable neuronal specializations that allow this pathway to represent most of the behaviorally relevant information available in sounds (Cant 1992; Rhode and Greenberg 1992; Romand and Avan 1997; Ryugo and Parks 2003). Because of the powerful influence that the developing ear exerts on the developing auditory central nervous system (CNS) (Rubel 1978; Parks 1997; Friauf and Lohmann 1999; Rubel and Fritzsch 2002), considerable research has been directed at understanding the basic events of normal development and the central effects of early deafness. The large literature on normal structural and functional development of the CN has been reviewed in a previous volume of this series (Cant 1998; Sanes and Walsh 1998), and various aspects of abnormal development are discussed in other chapters of the book (Friauf, Chapter 3 and Moore and King, Chapter 4).


cAMP Response Element Binding Cochlear Nucleus Cochlear Nerve Auditory Neuron Dorsal Cochlear Nucleus 
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© Springer Science+Business Media New York 2004

Authors and Affiliations

  • Edwin W. Rubel
  • Thomas N. Parks
  • Lance Zirpel

There are no affiliations available

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