Fibrinoid and Calcification

  • Kurt Benirschke
  • Peter Kaufmann


Fibrinoid has always played a remarkable role in the] literature of placental pathology. It is one of the most] prominent substances when studying the placenta microscopically or even in its macroscopic parameters. Fibrin is prominently involved in pathological processes, such as intervillous thrombosis and placental infarction, its quantity steadily increasing throughout pregnancy. Although the pathogenetic mechanism and diagnostic value of fibrinoid are still under discussion, it is one of the most frequently mentioned “histopathological” findings and is t therefore worthy of discussion in a special chapter.


Basal Plate Human Placenta Decidual Cell Intervillous Space Chorionic Plate 
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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • Kurt Benirschke
    • 1
    • 2
  • Peter Kaufmann
    • 3
  1. 1.Pathology and Reproductive MedicineUniversity of CaliforniaSan DiegoUSA
  2. 2.University Medical CenterSan DiegoUSA
  3. 3.Institut für Anatomie der Medizinischen Fakultät, Rheinisch-Westfälische TechnischeHochschule AachenAachenGermany

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