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Latices and Thermosensitive Gels as Sustained Delivery Systems to the Eye

  • R. Gurny
  • H. Ibrahim
  • T. Boye
  • P. Buri
Part of the FIDIA Research Series book series (FIDIA, volume 11)

Abstract

Traditionally, ophthalmic formulations have been limited to solutions or ointments and in some rare cases to emulsions or suspensions. An alternative is the use of carefully selected pH-sensitive polymeric materials dispersed in water in the nanometer size range as carriers or polymers with interesting sol-gel transition behavior. These two systems have been formulated and further investigated in order to slow down the extremely rapid drug exchange between the tear fluid and the medicament.

Keywords

Area Under Curve Mean Residence Time Polymeric Dispersion Nanometer Size Range Ophthalmic Formulation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1987

Authors and Affiliations

  • R. Gurny
    • 1
  • H. Ibrahim
    • 1
  • T. Boye
    • 1
  • P. Buri
    • 1
  1. 1.School of PharmacyUniversity of GenevaGeneva 4Switzerland

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