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Factors Influencing the Retention of Ophthalmic Solutions on the Eye Surface

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Ophthalmic Drug Delivery

Part of the book series: FIDIA Research Series ((FIDIA,volume 11))

Abstract

The instillation of an ophthalmic solution generally initiates reflex tears and reflex blinking, which attempt to remove quickly the instilled solution from the eye surface. Reflex tears and reflex blinking are often elicited by different properties of the instilled solutions, such as the instilled volume, the osmolality, the pH and viscosity of the solution, and also by the physical and chemical properties of the drugs and the adjuvants present.

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Authors and Affiliations

  1. Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, B-2610, Wilrijk, Belgium

    M. M. Van Ooteghem

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  1. M. M. Van Ooteghem
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Editor information

Editors and Affiliations

  1. Istituto di Chimica Farmaceutica, dell’Università di Pisa, Pisa, Italy

    Marco Fabrizio Saettone

  2. Clinica Oculistica, Università dell’Aquila, Pisa, Italy

    Massimo Bucci

  3. Pharmazeutisches Institut ETHZ, Zurich, Switzerland

    P. Speiser

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© 1987 Springer Science+Business Media New York

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Van Ooteghem, M.M. (1987). Factors Influencing the Retention of Ophthalmic Solutions on the Eye Surface. In: Saettone, M.F., Bucci, M., Speiser, P. (eds) Ophthalmic Drug Delivery. FIDIA Research Series, vol 11. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-4175-9_2

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  • DOI: https://doi.org/10.1007/978-1-4757-4175-9_2

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4757-4177-3

  • Online ISBN: 978-1-4757-4175-9

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