The application of recombinant DNA technology to human genetics has advanced our knowledge of inherited diseases immensely. Classical genetics was very limited in its ability to probe the complexity of the human genome. The famous genetic breeding experiments in viruses, bacteria, yeast, slime mold, and fruit flies taught us a great deal about genetics in general. However, applying classical genetics to human diseases was limited by our scant knowledge of human genes. Some people doubted that the science of human genetics would ever make much progress.* Recombinant DNA technology and genetic mapping have opened the very complex human genome to direct study.
KeywordsCystic Fibrosis Sickle Cell Anemia Sickle Cell Familial Hypercholesterolemia Sickle Cell Trait
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