In the first three chapters we have considered the basic principles and technology that underlie molecular medicine. This chapter on infectious diseases begins part 2, in which we will apply recombinant DNA technology to the study, diagnosis, and treatment of disease. For infectious diseases, the application of molecular medicine is both straightforward and dramatic. We can take any clinical sample and analyze it for the presence of foreign, nonhuman DNA. The source of the foreign DNA can be identified as to genus and species of the invading infectious agent.
KeywordsHepatitis Lymphoma Anemia Sarcoma Pseudomonas
Unable to display preview. Download preview PDF.
- Barker RH, Brandling-Bennett AD, Koech DK, Mugambi M, Khan B, David R, David JR, Wirth DF (1989) Plasmodium falciparum: DNA probe diagnosis of malaria in Kenya. Exp Parasitol 69: 226–233.Google Scholar
- Figueroa ME, Rasheed S (1991) Molecular pathology and diagnosis of infectious diseases. Am J Clin Pathol (Suppl) 95: S8 - S21.Google Scholar
- Munoz FJ, Sharon N (1990) Detection of human cytomegalovirus and Epstein-Barr Virus in peripheral blood mononuclear cells with DNA probes. Lab Med 21: 742–744.Google Scholar