Abstract
The radioimmunoassay (RIA) method was first developed by S.A. Berson and R.S. Yalow in the late 1950s for the determination of insulin in human serum. Currently, the method is employed extensively to determine numerous hormones, enzymes, antigens, and drugs in minute quantities (10-9-10-12 M) in human plasma in order to assess various disease conditions. The general term for this method in both immune and nonimmune systems is the competitive binding assay (CBA).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Suggested Reading
Andrews JT, Milne MJ. Nuclear Medicine. New York: Wiley; 1977.
Chase GC, Rabinowitz JL. Principles of Radioisotope Methodology. 3rd ed. Minneapolis: Burgess; 1970.
Hayes RL, Goswitz FA, Pearson Murphy BE, eds. Radioisotopes in medicine: In vitro studies. CONF-671111. US Atomic Energy Commission, Oak Ridge; 1972.
Kirkham KD, Hunter WM. Radioimmunoassay Methods. Baltimore: Williams & Wilkins; 1971.
Moss AJ Jr, Dalrymple GV, Boyd CM, eds. Practical Radioimmunoassay. St Louis: Mosby; 1976.
Odell WD, Daughaday WH, eds. Principles of Competitive Protein-Binding Assays. Philadelphia: Lippincott; 1974.
Rothfeld B, ed. Nuclear Medicine In Vitro. Philadelphia: Lippincott; 1974.
Thorell JI, Larson SM. Radioimmunoassay and Related Techniques. St Louis: Mosby; 1978.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 1992 Springer Science+Business Media New York
About this chapter
Cite this chapter
Saha, G.B. (1992). In Vitro and In Vivo Nonimaging Tests. In: Fundamentals of Nuclear Pharmacy. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-4027-1_11
Download citation
DOI: https://doi.org/10.1007/978-1-4757-4027-1_11
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4757-4029-5
Online ISBN: 978-1-4757-4027-1
eBook Packages: Springer Book Archive