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Radiopharmaceuticals

  • Gopal B. Saha

Abstract

A radiopharmaceutical is a radioactive compound used for the diagnosis and therapeutic treatment of human diseases. In nuclear medicine nearly 95 % of the radiopharmaceuticals are used for diagnostic purposes, while the rest are used for therapeutic treatment. Radiopharmaceuticals usually have no pharmacologic effect, because in most cases they are used in tracer quantities. In these cases, they do not show any dose—response relationship and thus differ from conventional drugs. Because they are administered to humans, they should be sterile and pyrogen free, and they should undergo all quality control measures required of a conventional drug. A radiopharmaceutical may be a radioactive element such as 133Xe or 85Kr, or a labeled compound such as 131I-iodinated proteins and 99mTc-labeled compounds.

Keywords

Plasma Clearance Label Compound Methylene Diphosphonate Coordinate Covalent Bond Nontarget Area 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Suggested Reading

  1. Burns HD (1978) Design of radiopharmaceuticals. In : Heindel ND, Burns HD, Honda T, Brady LW (eds) The chemistry of radiopharmaceuticals. Masson, New York, p 35Google Scholar
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  8. Wagner HN Jr, Stern HS, Rhodes BA, et al (1973) Design and development of new radiopharmaceuticals. In: Medical Radioisotope Scintigraphy, Vol 2. IAEA, Vienna, p 3Google Scholar

Copyright information

© Springer Science+Business Media New York 1979

Authors and Affiliations

  • Gopal B. Saha
    • 1
  1. 1.University of Arkansas for Medical SciencesLittle RockUSA

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