Oxygen Content, Delivery, and Uptake
Normal cellular function in the body is critically dependent on oxygen. Therefore, it is important for the body to be able to deliver oxygen to the cells and for the cells to utilize the oxygen once it has arrived. A change in either of these variables could lead to the development of cellular hypoxia and result in end-organ failure and possibly death. In many disease states, changes in oxygen delivery (DO2) and oxygen consumption (\(\dot V\)O2) are noted to occur and may be responsible for the clinical presentation of these patients. Meeting the metabolic demands of the cells is thus an important component of therapy in the critically ill patient.
KeywordsCardiac Output Oxygen Delivery Acute Respiratory Distress Syndrome Patient Arterial Lactate Blood Flow Distribution
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