Sex Cord-Stromal, Steroid Cell, and Other Ovarian Tumors with Endocrine, Paraendocrine, and Paraneoplastic Manifestations

  • Robert H. Young
  • Robert E. Scully


This category of ovarian neoplasms includes all those that contain granulosa cells, theca cells, and their luteinized derivatives; Sertoli cells; Leydig cells; and fibroblasts of gonadal stromal origin, singly or in various combinations and in varying degrees of differentiation.364,369,462,466,467,468 The generic terms that have been applied most widely to these tumors reflect differing views of gonadal embryology. Those who believe that all the above cell types are derived from the mesenchyme or “specialized stroma” of the genital ridge have proposed the terms “mesenchymomas”68 and “gonadal stromal tumors” for these neoplasms.301,305 In contrast, others, recognizing that many embryologists favor the participation of coelomic and mesonephric epithelium in the formation of the sex cords, which are the proximal precursors of granulosa cells and Sertoli cells, favor the terms sex cord-mesenchyrne tumors 286,366 and sex cord-stromal tumors.378.


Granulosa Cell Ovarian Tumor Leydig Cell Granulosa Cell Tumor Leydig Cell Tumor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Abeler V, Kjorstad KE, Nesland JM (1988) Small cell carcinoma of the ovary. A report of six cases. Int J Gynecol Pathol 7: 315–329PubMedCrossRefGoogle Scholar
  2. 2.
    Abell MR (1968) Undifferentiated malignant germ cell neoplasm (embyonal carcinoma) of the ovary with stromal luteinization. Am J Obstet Gynecol 101: 570–572PubMedGoogle Scholar
  3. 3.
    Abouav J, Berkowitz SB, Kolb FO (1959) Reversible hypercalcemia in masculinizing hypernephroid tumor of the ovary. Report of a case. N Engl J Med 260: 1057–1062PubMedCrossRefGoogle Scholar
  4. 4.
    Adeyemi SD, Grange AO, Giwa-Osagie OF, et al (1986) Adrenal rest tumor of the ovary associated with isosexual precocious pseudopuberty and cushingoid features. Eur J Pediatr 145: 236–238PubMedCrossRefGoogle Scholar
  5. 5.
    Aguirre P, Scully RE (1983) Testosterone-secreting adrenal ganglioneuroma containing Leydig cells. Am J Surg Pathol 7: 699PubMedCrossRefGoogle Scholar
  6. 6.
    Aguirre P, Scully RE, Delellis RA (1986) Ovarian heterologous Sertoli-Leydig cell tumors with gastrointestinal-type epithelium. An immunohsitochemical analysis. Arch Pathol Lab Med 110: 528–533.PubMedGoogle Scholar
  7. 7.
    Aguirre P, Thor AD, Scully RE (1989) Ovarian endometrioid carcinomas resembling sex cord-stromal tumors: An immunohistological study. Int J Gynecol Pathol 8: 364–373PubMedCrossRefGoogle Scholar
  8. 8.
    Aguirre P, Thor AD, Scully RE (1989) Ovarian small cell carcinoma—histogenetic considerations based on immunohistochemical and other findings. Am J Clin Pathol 92: 140–149PubMedGoogle Scholar
  9. 9.
    Ahn GH, Chi JG, Lee SK (1986) Ovarian sex cord tumor with annular tubules. Cancer 57: 1066–1073PubMedCrossRefGoogle Scholar
  10. 10.
    Aiba M, Hirayama A, Sakurada M, Naruse K, Ishikawa C, Aiba S (1990) Spironolactone rod-like structure in reninproducing Sertoli cell tumor of the ovary. Surg Pathol 3: 143–149Google Scholar
  11. 11.
    Aiman J, Forney JP, Parker CR (1986) Androgen and estrogen secretion by normal and neoplastic ovaries in premenopausal women. Obstet Gynecol 68: 327–332PubMedCrossRefGoogle Scholar
  12. 12.
    Aiman J, Nalick RH, Jacobs A, et al (1977) The origin of androgen and estrogen in a virilized postmenopausal woman with bilateral benign cystic teratomas. Obstet Gynecol 49: 695–704PubMedGoogle Scholar
  13. 13.
    Allan SG, Lockhart SP, Leonard RCF, Smyth JF (1984) Paraneoplastic hypercalcemia in ovarian carcinoma. Br Med J 288: 1714–1715CrossRefGoogle Scholar
  14. 14.
    Allander E, Wagermark J (1969) Leydig cell tumors of the ovary. Report of three cases. Acta Obstet Gynecol Scand 48: 433PubMedCrossRefGoogle Scholar
  15. 15.
    Alvarez RD, Varner RE (1987) Hyperandrogenic state associated with a mucinous cystadenoma. Obstet Gynecol 69: 507–510PubMedGoogle Scholar
  16. 16.
    Anderson MC (1972) Hilar cell tumour of the ovary. J Clin Pathol 25: 106PubMedCrossRefGoogle Scholar
  17. 17.
    Anderson MC, Rees DA (1975) Gynandroblastoma of the ovary. Br J Obstet Gynaecol 82: 68PubMedCrossRefGoogle Scholar
  18. 18.
    Anderson PW, Macaulay L, Do YS, et al (1989) Extrarenai renin-secreting tumors: Insights into hypertension and ovarian renin production. Medicine 68: 257–268PubMedCrossRefGoogle Scholar
  19. 19.
    Andujar JJ, Enloe GR, Swift WB (1947) Brenner tumor of the ovary; 2 cases associated with postmenopausal endometrial changes. Texas J Med 43: 70–75PubMedGoogle Scholar
  20. 20.
    Anikwue C, Dawood MY, Kramer E (1979) Granulosa and theca cell tumors. Obstet Gynecol 51: 214–220Google Scholar
  21. 21.
    Anstey JT, Blythe JG (1972) Fibrin degradation products and the diagnosis of ovarian carcinoma. Obstet Gynecol 52: 605–608Google Scholar
  22. 22.
    Arai N, Misugi K, Kamiya T, Shima S (1988) An ovarian Sertoli-Leydig cell tumor with heterologous mucinous gland and NSE-immunoreactive-cell. Arch Gynecol Obstet 243: 55–60PubMedCrossRefGoogle Scholar
  23. 23.
    Armstrong DT, Papkoff H (1976) Stimulation of aromatization by endogenous and exogenous androgens in ovaries of hypophysectomized rats in vivo by FSH. Endocrinology 99: 1144–1151PubMedCrossRefGoogle Scholar
  24. 24.
    Astedt B, Svanberg L, Nilsson IM (1971) Fibrin degradation products and ovarian tumours. Br Med J 4: 458–459PubMedCrossRefGoogle Scholar
  25. 25.
    Astengo-Osuna C (1984) Ovarian sex-cord tumor with annular tubules. Case report with ultrastructural findings. Cancer 54: 1070–1075PubMedCrossRefGoogle Scholar
  26. 26.
    Atlas SA, Sherman RL, Pasmantier MW, et al (1982) Response of active and inactive renins, aldosterone and blood pressure to chemotherapy in a patient with a possible renin-secreting ovarian carcinoma. Clin Res 30: 333A (abstr)Google Scholar
  27. 27.
    Axiotis CA, Lippes HA, Merino MJ, de Lanerolle NC, Stewart AF, Kinder B (1987) Corticotroph cell pituitary adenoma within an ovarian teratoma. A new cause of Cushing’s syndrome. Am J Surg Pathol 11: 218–224PubMedCrossRefGoogle Scholar
  28. 28.
    Backstrom T, Mahlck C, Kjellgren O (1983) Progesterone as a possible tumor marker for “nonendocrine” ovarian malignant tumors. Gynecol Oncol 16: 129–138PubMedCrossRefGoogle Scholar
  29. 29.
    Baker LRI, Brain MC, Azzopardi JG, Worlledge SM (1968) Autoimmune haemolytic anaemic associated with ovarian dermoid cyst. J Clin Pathol 21: 626PubMedCrossRefGoogle Scholar
  30. 30.
    Balasa RW, Adcock LL, Prem KA, Dehner LP (1977) The Brenner tumor. Obstet Gynecol 50: 120–128PubMedGoogle Scholar
  31. 31.
    Banner EA, Dockerty MB (1945) Theca cell tumors of the ovary. A clinical and pathological study of twenty-three cases (including thirteen new cases) with a review. Surg Gynecol Obstet 81: 234–242Google Scholar
  32. 32.
    Baramki TA, Leddy AL, Woodruff JD (1983) Bilateral hilus cell tumors of the ovary. Obstet Gynecol 62: 128–131PubMedGoogle Scholar
  33. 33.
    Barnes BE (1976) Dermatomyositis and malignancy. A review of the literature. Ann Intern Med 84: 68–76PubMedGoogle Scholar
  34. 34.
    Beauchamp PJ, Hughes RS, Schmidt WA (1989) Virilizing serous cystadenoma. Obstet Gynecol 73: 513–517PubMedGoogle Scholar
  35. 35.
    Beck JS, Fulman HF, Lee ST (1969) Solid malignant ovarian teratoma with ‘embryoid bodies’ and trophoblastic differentiation. J Pathol 99: 67–73PubMedCrossRefGoogle Scholar
  36. 36.
    Bell RJM (1977) Fetal virilisation due to maternal Krukenberg tumour. Lancet 1: 1162–1163PubMedCrossRefGoogle Scholar
  37. 37.
    Benagiano G, Bigotti G, Buzzi M, et al (1988) Endocrine and morphological study of case of ovarian sex-cord tumor with annular tubules in a woman with Peutz-Jeghers syndrome. Int J Gynecol Obstet 26: 441–452CrossRefGoogle Scholar
  38. 38.
    Benfield GFA, Tapper-Jones L, Stout TV (1982) Androblastoma and raised serum alpha-fetoprotein with familial multinodular goitre. Case report. Br J Obstet Gynaecol 89: 323PubMedCrossRefGoogle Scholar
  39. 39.
    Benjamin E, Law S, Bobrow LG (1987) Intermediate filament cytokeratin and vimentin in ovarian sex cord-stromal tumors with correlative studies in adult and fetal ovaries. J Pathol 152: 253–263PubMedCrossRefGoogle Scholar
  40. 40.
    Bennett RM, Ginsberg MH, Thomsen S (1976) Carcinomatous polyarthritis. Arthritis Rheum 19: 953–959PubMedCrossRefGoogle Scholar
  41. 41.
    Bennington JL, Ferguson BR, Haber SL (1968) Incidence and relative frequency of benign and malignant ovarian neoplasms. Obstet Gynecol 32: 627–732PubMedGoogle Scholar
  42. 42.
    Berlin N1, Van Scott EJ, Clendenning WE, et al (1966) Basal cell nevus syndrome. Ann Intern Med 64: 403PubMedGoogle Scholar
  43. 43.
    Bernstein D, Naor S, Rikover M, Menahem H (1974) Hemolytic anemia related to ovarian tumor. Obstet Gynecol 43: 276–280PubMedGoogle Scholar
  44. 44.
    Besch PK, Byron RC, Barry RD, et al (1963) Testosterone synthesis by a Brenner tumor. Part II. In vitro biosynthetic steroid conversion of a Brenner tumor. Am J Obstet Gynecol 86: 1021–1026PubMedGoogle Scholar
  45. 45.
    Betta P, Bellingeri D (1985) Androgenic juvenile granulosa cell tumor. Case report. Eur J Gynaecol Oncol 6: 71–74PubMedGoogle Scholar
  46. 46.
    Bettinger JF, Jacobs H (1946) A contribution to the problem of masculinization. Med J Aust 1: 10–13PubMedGoogle Scholar
  47. 47.
    Bjorkholm E (1980) Granulosa cell tumors: A comparison of survival in patients and matched controls. Am J Obstet Gynecol 138: 329–331PubMedGoogle Scholar
  48. 48.
    Bjorkholm E, Pettersson F (1980) Granulosa-cell and theca-cell tumors. The clinical picture and long term outcome for the Radiumhemmet series. Acta Obstet Gynec Scand 59: 361PubMedCrossRefGoogle Scholar
  49. 49.
    Bjorkholm E, Silfversward C (1981) Prognostic factors in granulosa cell tumors. Gynecol Oncol 11: 261PubMedCrossRefGoogle Scholar
  50. 50.
    Bjorkholm E, Silfversward C (1980) Theca-cell tumors. Clinical features and prognosis. Acta Radiol Oncol Radiat Phys Biol 19: 241CrossRefGoogle Scholar
  51. 51.
    Bohm J, Roder-Weber M, Hofier H (1991) Bilateral stromal Leydig cell tumor of the ovary. Case report and literature review. Path Res Pract 187: 348–352PubMedCrossRefGoogle Scholar
  52. 52.
    Boivin Y, Richart RM (1965) Hilus cell tumors of the ovary. A review with a report of 3 new cases. Cancer 18: 231PubMedCrossRefGoogle Scholar
  53. 53.
    Boixeda D, Roman AL, Pascasio JM, et al (1990) Zollinger-Ellison syndrome due to gastrin-secreting ovarian cystadenocarcinoma. Case report. Acta Chir Scand 156: 409–410PubMedGoogle Scholar
  54. 54.
    Bollen ECM, Lamers CBHW, Jansen JMBJ, et al (1981) Zollinger-Ellison syndrome due to a gastrin-producing ovarian cystadenocarcinoma. Br J Surg 68: 776–777PubMedCrossRefGoogle Scholar
  55. 55.
    Bonaventura LM, Judd H, Roth LM, Cleary RE (1978) Androgen, estrogen, and progesterone production by a lipid cell tumor of the ovary. Am J Obstet Gynecol 131: 403PubMedGoogle Scholar
  56. 56.
    Borushek S, Berger I, Echt C, Gold JJ (1965) Functioning malignant germ cell tumor of the ovary in a 4?-year-old girl. Cancer 18: 1485–1488PubMedCrossRefGoogle Scholar
  57. 57.
    Boss JH, Scully RE, Wegner KH, Cohen RB (1965) Structural variations in the adult ovary—clinical significance. Obstet Gynecol 25: 747–764PubMedGoogle Scholar
  58. 58.
    Bower JF, Erickson ER (1967) Bilateral ovarian fibromas in a 5-year-old. Am J Obstet Gynecol 99: 880PubMedGoogle Scholar
  59. 59.
    Brain Lord (1963) The neurological complications of neoplasms. Lancet 1: 179–184PubMedCrossRefGoogle Scholar
  60. 60.
    Bronstein R, Hardouin G, Henrion R (1972) Kyste mucoide virilisant au cours de la grossesse. J Gynecol Obstet Biol Reprod 1: 891–899Google Scholar
  61. 61.
    Brown H, Lane M (1965) Cushing’s and malignant carcinoid syndromes from ovarian neoplasm. Arch Intern Med 115: 490–494PubMedCrossRefGoogle Scholar
  62. 62.
    Brown WW, Shetty KR, Rosenfeld PS (1973) Hyperthyroidism due to struma ovarii: Demonstration by radioiodine scan. Acta Endocrinol 73: 266–272PubMedGoogle Scholar
  63. 63.
    Bruno MS, Ober WB (1959) Clincopathologic Conference. N Y State J Med 59: 4001–4007Google Scholar
  64. 64.
    Bullon A, Arseneau J, Prat J, Young RH, Scully RE (1981) Tubular Krukenberg tumor. A problem in histopathologic diagnosis. Am J Surg Pathol 5: 225–232PubMedCrossRefGoogle Scholar
  65. 65.
    Burket RL, Rauh JL (1976) Gorlin’s syndrome: Ovarian fibromas at adolescence. Obstet Gynecol 47: 43s–44sPubMedGoogle Scholar
  66. 66.
    Burslem RW, Langley FA, Woodcock AS (1954) A clincopathological sutdy of oestrogenic ovarian tumors. Cancer 7: 552CrossRefGoogle Scholar
  67. 67.
    Burton PBJ, Knight DE, Quirke P, et al (1990) Parathyroid hormone related peptide in ovarian carcinoma. J Clin Pathol 43: 784PubMedCrossRefGoogle Scholar
  68. 68.
    Busby T, Anderson GW (1954) Feminizing mesenchymomas of the ovary. Am J Obstet Gynecol 68: 1391PubMedGoogle Scholar
  69. 69.
    Calabro JJ (1967) Cancer and arthritis. Arthritis Rheum 10: 553–567PubMedCrossRefGoogle Scholar
  70. 70.
    Callen JP (1986) Dermatomyositis and female malignancy. J Surg Oncol 32: 121–124PubMedCrossRefGoogle Scholar
  71. 71.
    Campbell PE, Danks DM (1963) Pseudoprecocity in an infant due to a luteoma of the ovary. Arch Dis Child 38: 519PubMedCrossRefGoogle Scholar
  72. 72.
    Cannon PM, Smart CR, Wilson ML, Edwards CB (1975) Hypercalcemia with ovarian granulosa cell carcinoma. Rocky Mountain Med J 72: 72–74PubMedGoogle Scholar
  73. 73.
    Carlstrom K, Lagrelius A, von Schoultz B (1985) Serum levels of dehydroepiandrosterone sulphage and total estrone in postmenopausal women with special regard to ‘non-endocrine’ ovarian carcinoma. Acta Obstet Gynecol Scand 64: 267–268PubMedCrossRefGoogle Scholar
  74. 74.
    Caron P, Roche H, Gorguet B, Martel P, Bennet A, Carton M (1990) Mammary ovarian metastases with stroma cell hyperplasia and postmenopausal virilization. Cancer 66: 1221–1224PubMedCrossRefGoogle Scholar
  75. 75.
    Carreras Vescio LA, Toblli JE, Rey JA, Assai ME, De Maria HE, Marietta J (1983) Autoimmune hemolytic anemia associated with an ovarian neoplasm. Medicina 43: 415–424PubMedGoogle Scholar
  76. 76.
    Case Records of the Massachusetts General Hospital (1970) Case 13–1970. N Engl J Med 282: 676–681CrossRefGoogle Scholar
  77. 77.
    Case Records of the Massachusetts General Hospital (1972) Case 11–1972. N Engl J Med 286: 594–600CrossRefGoogle Scholar
  78. 78.
    Case Records of the Massachusetts General Hospital (1975) Case 10,1975. N Engl J Med 292: 521CrossRefGoogle Scholar
  79. 79.
    Case Records of the Massachusetts General Hospital (1976) Case 14,1976. N Engl J Med 294: 772CrossRefGoogle Scholar
  80. 80.
    Case Records of the Massachusetts General Hospital (1976) Case 26–1976. N Engl J Med 294: 1447–1454CrossRefGoogle Scholar
  81. 81.
    Case Records of the Massachusetts General Hospital (1978) Case 13,1978. N Engl J Med 298: 786–792CrossRefGoogle Scholar
  82. 82.
    Case Records of the Massachusetts General Hospital (1983) Case 21–1983. N Engl J Med 308: 1279–1284CrossRefGoogle Scholar
  83. 83.
    Case Records of the Massachusetts General Hospital (1985) Case 30–1985. N Engl J Med 313: 249–257.CrossRefGoogle Scholar
  84. 84.
    Cashell AW, Cohen ML (1991) Masculinizing sclerosing stromal tumor of the ovary during pregnancy. Gynecol Oncol 43: 281–285PubMedCrossRefGoogle Scholar
  85. 85.
    Casper S, van Nagell JR, Powell DF, et al (1981) Immuno-histochemical localization of tumor markers in epithelial ovarian cancer. Am J Obstet Gynecol 149: 154–158Google Scholar
  86. 86.
    Chadha S, van der Kwast TH (1989) Immunohistochemistry of ovarian granulosa cell tumors. The value of tissue specific proteins and tumor markers. Virchows Arch (A) 414: 439–445CrossRefGoogle Scholar
  87. 87.
    Chalvardjian A, Derzko C (1982) Gynandroblastoma. Its ultrastructure. Cancer 50: 710PubMedCrossRefGoogle Scholar
  88. 88.
    Chalvardjian A, Scully RE (1973) Sclerosing stromal tumors of the ovary. Cancer 31: 664PubMedCrossRefGoogle Scholar
  89. 89.
    Chan LKC, Prathap K (1970) Virilization in pregnancy associated with an ovarian mucinous cystadenoma. Am J Obstet Gynecol 108: 946–949PubMedGoogle Scholar
  90. 90.
    Chen KTK (1986) Female genital tract tumors in PeutzJeghers syndrome. Hum Pathol 17: 858–861PubMedCrossRefGoogle Scholar
  91. 91.
    Christian E (1910) Un Cas d’epitheliome a granulations de luteine d’origine probablement ovarienne. Soc Anat Ann 12: 639–641Google Scholar
  92. 92.
    Christman JE, Ballon SC (1990) Ovarian fibrosarcoma associated with Maffucci’s syndrome. Gynecol Oncol 37: 290–291PubMedCrossRefGoogle Scholar
  93. 93.
    Chumas JC, Rosenwaks Z, Mann WJ, Finkel G, Pastore J (1984) Sertoli-Leydig cell tumor of the ovary producing alpha-fetoprotein. Int J Gynecol Pathol 3: 213–219PubMedCrossRefGoogle Scholar
  94. 94.
    Civantos F, Rywlin AM (1972) Carcinomas with trophoblastic differentiation and secretion of chroionic gonadot-rophins. Cancer 29: 789–798PubMedCrossRefGoogle Scholar
  95. 95.
    Clement PB, Scully RE (1980) Large solitary luteinized follicle cyst of pregnancy and puerperium. A clinico-pathological analysis of eight cases. Am J Surg Pathol 4: 431–138PubMedCrossRefGoogle Scholar
  96. 96.
    Clement PB, Young RH, Scully RE (1991) Clinical syndromes associated with tumors of the female genital tract. Semin Diagn Pathol 8: 204–233PubMedGoogle Scholar
  97. 97.
    Clement PB, Young RH, Scully RE (1988) Ovarian granulosa cell proliferations of pregnancy: A report of nine cases. Hum Pathol 19: 657–662PubMedCrossRefGoogle Scholar
  98. 97a.
    Clement PB, Young RH, Hanna W, Scully RE (1994) Sclerosing peritonitis associated with lutenized thecomas of the ovary. A clinicopathological analysis of six cases. Am J Surg Pathol 18: 1–13.PubMedCrossRefGoogle Scholar
  99. 98.
    Cocco AE, Conway SJ (1975) Zollinger-Ellison syndrome associated with ovarian mucinous cystadenocarcinoma. N Engl J Med 293: 485–486PubMedCrossRefGoogle Scholar
  100. 99.
    Cocconi G, Ceci G, Juvarra G, et al (1985) Successful treatment of subacute cerebellar degeneration in ovarian carcinoma with plasmapheresis. A case report. Cancer 56: 2318–1320PubMedCrossRefGoogle Scholar
  101. 100.
    Cohen PR, Kohn SR, Kurzrock R (1991) Association of sebaceous gland tumors and internal malignancy: The Muir-Torre syndrome. Am J Med 90: 606–613PubMedGoogle Scholar
  102. 101.
    Connor TB, Ganis FM, Levin HS, Migeon CJ, Martin LG (1968) Gonadotropin-dependent Krukenberg tumor causing virilization during pregnancy. J Clin Endocrinol Metab 28: 198–214PubMedCrossRefGoogle Scholar
  103. 102.
    Cotton DH, Hanson FW, Oi RH (1981) A mucinous cystadenoma associated with testosterone production. J Reprod Med 26: 276–278PubMedGoogle Scholar
  104. 103.
    Croft PB, Wilkinson M (1965) The incidence of carcino-matous neuromyopathy in patients with various types of carcinoma. Brain 88: 427–434PubMedCrossRefGoogle Scholar
  105. 104.
    Curth HO, Hilberg AW, Machacek GF (1962) The site and histology of the cancer associated with malignant acanthosis nigricans. Cancer 15: 364–382PubMedCrossRefGoogle Scholar
  106. 105.
    Czernobilsky B (1984) Immunohistochemistry of normal tissues of the female genital tract. Presentation at XVth International Congress of International Academy of Pathology, Miami Beach, FL.Google Scholar
  107. 106.
    DaCosta CC (1938) Tumor masculinizante. Rev Gynecol Obstet 2: 3–9Google Scholar
  108. 107.
    Dales M (1965) Purpura associated with ovarian tumor. Br Med J 1: 127PubMedCrossRefGoogle Scholar
  109. 108.
    Damjanov I, Drobnjak P, Grizelj V, Longhino N (1975) Sclerosing stromal tumor of the ovary. A hormonal and ultrastructural analysis. Obstet Gynecol 45: 675–679CrossRefGoogle Scholar
  110. 109.
    Dardi LE, Miller AW, Gould VE (1982) Sertoli-Leydig cell tumor with endometrioid differentiation. Case report and discussion of histogenesis. Diagn Gynecol Obstet 4: 227–234PubMedGoogle Scholar
  111. 110.
    Davidson BJ, Waisman J, Judd HL (1981) Long-standing virilism in a woman with hyperplasia and neoplasia of ovarian lipidic cells. Obstet Gynecol 58: 753–759PubMedGoogle Scholar
  112. 111.
    Dawson MA, Talbert W, Yarbro JW (1971) Hemolytic anemia associated with an ovarian tumor. Am J Med 50: 552PubMedCrossRefGoogle Scholar
  113. 112.
    DeBruyere M, Sokal G, Devoitille JM, Fauchet-Dutrieux MC, De Spa V (1971) Autoimmune haemolytic anaemia and ovarian tumour. Br J Haemat 20: 83CrossRefGoogle Scholar
  114. 113.
    Delgado G, Smith JP (1975) Gynecological malignancy associated with non-bacterial thrombotic endocarditis (NBTE). Gynecol Oncol 3: 205–209PubMedCrossRefGoogle Scholar
  115. 114.
    de Lima GR, de Lima OA, Baracat EC, Vasserman J, Burnier M (1989) Virilizing Brenner tumor of the ovary: Case report. Obstet Gynecol 73: 895–898PubMedGoogle Scholar
  116. 115.
    DeTorres EF (1974) Feminization in tumors of Sertoli-Leydig cells. Acta Cytol 18: 187Google Scholar
  117. 116.
    Dickersin GR, Kline IW, Scully RE (1982) Small cell carcinoma of the ovary with hypercalcemia. A report of eleven cases. Cancer 49: 188PubMedCrossRefGoogle Scholar
  118. 117.
    Dikman SH, Toker C (1971) Strumal carcinoid of the ovary with masculinization. Cancer 27: 925–930PubMedCrossRefGoogle Scholar
  119. 118.
    Diddle AW (1951) Granulosa-and theca-cell ovarian tumors: Prognosis. Cancer 15: 215–228Google Scholar
  120. 119.
    Dingley ER, Marten RH (1957) Adenocarcinoma of the ovary presenting as acanthosis nigricans. J Obstet Gynaecol Br Commonw 64: 898–900CrossRefGoogle Scholar
  121. 120.
    Disaia PJ, Saltz A, Kagan AR, Rich W (1978) A temporary response of recurrent granulosa cell tumor to adriamycin. Obstet Gynecol 52: 355PubMedGoogle Scholar
  122. 121.
    Dockerty MB, MacCarty WC (1939) Granulosa cell tumors; with the report of a 34-lb specimen and a review. Am J Obstet Gynecol 37: 425Google Scholar
  123. 122.
    Dockerty MB, Masson JC (1944) Ovarian fibromas: A clinical and pathologic study of two hundred and eighty-three cases. Am J Obstet Gynecol 47: 741Google Scholar
  124. 123.
    Dorrington JH, Moon YS, Armstrong DT (1975) Estradiol-17B biosynthesis in cultured granulosa cells from hypophy-sectomized immature rats: Stimulation by FSH. Endocrinology 97: 1328–1331PubMedCrossRefGoogle Scholar
  125. 124.
    Dunaif A, Hoffman AR, Scully RE, et al (1985) Clinical, biochemical, and ovarian morphologic features in women with acanthosis nigricans and masculinization. Obstet Gynecol 66: 545–552PubMedGoogle Scholar
  126. 125.
    Duncan SC, Winkelmann RK (1979) Cancer and scleroderma. Arch Dermatol 115: 950–955PubMedCrossRefGoogle Scholar
  127. 126.
    Dunnihoo DR, Grieme DL, Woolf RB (1966) Hilar-cell tumors of the ovary. Report of 2 new cases and a review of the world literature. Obstet Gynecol 27: 703PubMedGoogle Scholar
  128. 127.
    Echt CR, Hadd HE (1968) Androgen excretion patterns in a patient with a metastatic hilus cell tumor of the ovary. Am J Obstet Gynecol 100: 1055PubMedGoogle Scholar
  129. 128.
    Eddie DAS (1967) Hormonal activity with ovarian tumours. J Obstet Gynaecol Br Commonw 74: 283–285PubMedCrossRefGoogle Scholar
  130. 129.
    Ehrlich EN, Dominguez OV, Samuels LT, Lynch D, Oberhelman H, Warner NE (1963) Aldosteronism and precocious puberty due to an ovarian androblastoma (Sertoli cell tumor). J Clin Endocrinol Metab 23: 358–367CrossRefGoogle Scholar
  131. 130.
    Eichhorn JH, Bell DA, Young RH, et al (1992) DNA content and proliferative activity in ovarian small cell carcinomas of the hypercalcemic type. Implications for diagnosis, prognosis and histogenesis. Am J Clin Pathol 98: 579–586PubMedGoogle Scholar
  132. 131.
    Emig OR, Hertig AT, Rowe FJ (1959) Gynandroblastoma of the ovary. Review and report of a case. Obstet Gynecol 13: 135PubMedCrossRefGoogle Scholar
  133. 132.
    Evans AT, Gaffey TA, Malkasian GD Jr, Annegers JF (1980) Clinicopathologic review of 118 granulosa and 82 theca cell tumors. Obstet Gynecol 55: 231PubMedGoogle Scholar
  134. 133.
    Falls JL (1955) Accessory adrenal cortex in the broad ligament. Incidence and functional significance. Cancer 8: 143PubMedCrossRefGoogle Scholar
  135. 134.
    Fathalla MF (1967) The occurrence of granulosa and theca tumors in clinically normal ovaries. A study of 25 cases. J Obstet Gynaecol Br Commonw 74: 279CrossRefGoogle Scholar
  136. 135.
    Fathalla MF (1968) The role of the ovarian stroma in hormone production by ovarian tumors. J Obstet Gynaecol Br Commonw 75: 78–83PubMedCrossRefGoogle Scholar
  137. 136.
    Fathizadeh A, Medenica MM, Soltani K, et al (1982) Aggressive keratoacanthoma and internal malignant neoplasm. Arch Dermatol 118: 112–114PubMedCrossRefGoogle Scholar
  138. 137.
    Fawcett FJ, Kimbell NKB (1971) Phaeochromocytoma of the ovary. J Obstet Gynaecol Br Commonw 78: 458–459PubMedCrossRefGoogle Scholar
  139. 138.
    Fayez JA, Bunch TR, Miller GL (1974) Virilization in pregnancy associated with an ovarian serous cystadenoma. Am J Obstet Gynecol 120: 341–346PubMedGoogle Scholar
  140. 139.
    Fenoglio CM, Hayata T, Crum CP, Richart RM (1982) The expression of human chorionic gonadotrophin in the female genital tract. Localization by the immunoperoxidase technique. Diagn Gynecol Obstet 4: 94–97Google Scholar
  141. 140.
    Ferenczy A, Okagaki T, Richart RM (1971) Para-endocrine hypercalcemia in ovarian neoplasms. Report of mesonephroma with hypercalcemia and review of literature. Cancer 27: 427–433PubMedCrossRefGoogle Scholar
  142. 141.
    Ferenczy A, Richart RM (1974) Female reproductive system: Dynamics of scan and transmission electron microscopy. New York, John Wiley amp; Sons.Google Scholar
  143. 141a.
    Ferry JA, Young RH, Engel G, Scully RE (in press) Oxyphilic sertoli cell tumor of the ovary: A report of three cases, two in patients with the Peutz-Jeghers Syndrome. Int J Gynecol Pathol.Google Scholar
  144. 142.
    Fetissof F, Berger G, Dubois MP, et al (1985) Female genital tract and Peutz-Jeghers syndrome: An immunohis-tochemical study. Int J Gynecol Pathol 4: 219–229PubMedCrossRefGoogle Scholar
  145. 142a.
    Fleischhacker DS, Young RH (in press) Dysgerminoma of the ovary associated with hypercalcemia. Gynecol Oncol.Google Scholar
  146. 143.
    Forest MG, Orgiazzi J, Tranchant D, Mornex R, Bertrand J (1978) Approach to the mechanism of androgen overproduction in a case of Krukenberg tumor responsible for virilization during pregnancy. J Clin Endocrinol Metab 47: 428–434PubMedCrossRefGoogle Scholar
  147. 145.
    Fox H (1965) Estrogenic activity of the serous cystadenoma of the ovary. Cancer 18: 1041–1047PubMedCrossRefGoogle Scholar
  148. 144.
    Fox H, Agrawal K, Langley FA (1975) A clinicopathological study of 92 cases of granulosa cell tumor of the ovary with special reference to the factors influencing prognosis. Cancer 35: 231PubMedCrossRefGoogle Scholar
  149. 145.
    Fox LP, Stamm WJ (1965) Krukenberg tumor complicating pregnancy. Report of a case with androgenic activity. Am J Obstet Gynecol 92: 702–710PubMedGoogle Scholar
  150. 147.
    Franke WW, Grund C, Schmid E (1979) Intermediatesized filaments in Sertoli are of vimentin-type. Eur J Cell Biol 19: 269–275PubMedGoogle Scholar
  151. 148.
    Fujino T, Watanabe T, Yamaguchi K, et al (1992) The development of hypercalcemia in a patient with an ovarian tumor producing parathyroid hormone-related protein. Cancer 70: 2845–2850PubMedCrossRefGoogle Scholar
  152. 149.
    Fung MFK, Vadas G, Lotocki R, Heywood M, Krepart G (1991) Tubular Krukenberg tumor in pregnancy with virilization. Gynecol Oncol 41: 81–84PubMedCrossRefGoogle Scholar
  153. 150.
    Gaffney EF, Majmudar B, Hertzler GL, Zane R, Furlong B, Breding E (1983) Ovarian granulosa cell tumors—im-munohistochemical localization of estradiol and ultrastructure, with functional correlations. Obstet Gynecol 61: 311–318PubMedGoogle Scholar
  154. 151.
    Gagnon S, Tetu B, Silva EG, McCaughey WTE (1989) Frequency of α-fetoprotein production by Sertoli-Leydig cell tumors of the ovary: an immunohistochemical study of eight cases. Mod Pathol 2: 6S–67Google Scholar
  155. 152.
    Garcia-Villaneuva M, Figuerola NB, del Arbol LR, Ortiz MJH (1990) Zollinger-Ellison syndrome due to a borderline mucinous cystadenoma of the ovary. Obstet Gynecol 75: 549–551Google Scholar
  156. 153.
    Garneau R, Cabanne F (1968) Dysembryome ovarien de type enteroide et bilio-Berger. A propos d’une observation. Ann Anat Pathol 13: 423–432Google Scholar
  157. 154.
    Gee DC, Russell P (1979) Sclerosing stromal tumours of the ovary. Histopathology 3: 367–376PubMedCrossRefGoogle Scholar
  158. 155.
    Gee DC, Russell P (1981) The pathological assessment of ovarian neoplasms. IV: The sex cord stromal tumors. Pathology 13: 235–255PubMedCrossRefGoogle Scholar
  159. 156.
    Geist SH, Gaines JA (1938) Theca cell tumors. Am J Obstet Gynecol 35: 39–51Google Scholar
  160. 157.
    Genton CY (1980) Ovarian Sertoli-Leydig cell tumors. A clinical, pathological and ultrastructural study with particular reference to the histogenesis of these tumors. Arch Gynecol 230: 49–75PubMedCrossRefGoogle Scholar
  161. 158.
    Genton CY (1980) Some observations on the fine structure of human granulosa cell tumors. Virchows Arch A Path Anat Histol 387: 353–369CrossRefGoogle Scholar
  162. 159.
    Ghio R, Haupt E, Ratti M, Boccaccio P (1981) Erythrocytosis associated with a dermoid cyst of the ovary and erythropoietic activity of the tumour fluid. Scand J Haematol 27: 70–74PubMedCrossRefGoogle Scholar
  163. 160.
    Givens JR (1976) Hirsutism and hyperandrogenism. Adv Intern Med 21: 221–247PubMedGoogle Scholar
  164. 161.
    Givens JR, Kerber IJ, Wiser WL, Anderson RW, Coleman SA, Fish SA (1974) Remission of acanthosis nigricans associated with polycystic ovarian disease and a stromal luteoma. J Clin Endocrinol Metab 38: 347PubMedCrossRefGoogle Scholar
  165. 162.
    Glaser D, Nienhaus H, Köhler R, Walther G, Pawlowitzki IH (1988) A sex cord stromal tumour in a woman with XO/XX/XXX-mosaicism. Arch Gynecol Obstet 243: 115–118PubMedCrossRefGoogle Scholar
  166. 163.
    Goldberg B, Seegar Jones GE, Woodruff JD (1963) A histochemical study of steroid 3β-ol dehydrogenase activity in some steroid-producing tumors. Am J Obstet Gynecol 86: 1003–1014PubMedGoogle Scholar
  167. 164.
    Gondos B, Monroe SA (1971) Cystic granulosa cell tumor with massive hemoperitoneum. Light and electron microscopic study. Obstet Gynecol 38: 683–689PubMedGoogle Scholar
  168. 165.
    Gorlin RJ (1987) Nevoid basal-cell carcinoma syndrome. Medicine 66: 98–113PubMedCrossRefGoogle Scholar
  169. 166.
    Gorlin RJ, Sedano HO (1971) The multiple nevoid basal cell carcinoma syndrome revisited. Birth Defects 7: 140PubMedGoogle Scholar
  170. 167.
    Gorlin RJ, Vickers RA, Kelln E, Williamson JJ (1965) The multiple basal cell nevi syndrome. Cancer 18: 89PubMedCrossRefGoogle Scholar
  171. 168.
    Graham R, McKee P, McGibbon D, et al (1985) Torre-Muir syndrome. An association with isolated sebaceous carcinoma. Cancer 55: 2868–2873PubMedCrossRefGoogle Scholar
  172. 169.
    Greco MA, LiVolsi VA, Pertschuk KP, Bigelow B (1979) Strumal carcinoid of the ovary. An analysis of its components. Cancer 43: 1380–1388PubMedCrossRefGoogle Scholar
  173. 170.
    Greenlee JE, Brashear HR (1983) Antibodies to cerebellar Purkinje cells in patients with paraneoplastic cerebellar degeneration and ovarian carcinoma. Ann Neurol 14: 609–613PubMedCrossRefGoogle Scholar
  174. 171.
    Grenet P, Badoual J, Gallet JP, et al (1972) Dyschondro-plasie et tumeur de l’ovaire. Ann Pediatr (Paris) 19: 759–764Google Scholar
  175. 172.
    Guerard MJ, Ferenczy A, Arguelles MA (1982) Ovarian Sertoli-Leydig cell tumor with rhabdomyosarcoma: An ultrastructural study. Ultrastruct Pathol 3: 347PubMedCrossRefGoogle Scholar
  176. 173.
    Guintoli RL, Celebre JA, Wu CH, Wheeler JE, Mikuta JJ (1976) Androgenic function of a granulosa cell tumor. Obstet Gynecol 47: 77Google Scholar
  177. 174.
    Gusberg SB, Kardon P (1967) Proliferative endometrial response to theca-granulosa cell tumors. Am J Obstet Gynecol 111: 633Google Scholar
  178. 175.
    Gustafson ML, Lee MM, Scully RE, et al (1992) Mullerian inhibiting substance as a marker for ovarian sex-cord tumor. N Engl J Med 326: 466–471PubMedCrossRefGoogle Scholar
  179. 176.
    Hall DJ, Dyer ML, Parker JC (1985) Ovarian cancer complicated by cerebellar degeneration: A paraneoplastic syndrome. Gynecol Oncol 21: 240–246PubMedCrossRefGoogle Scholar
  180. 177.
    Hameed H (1972) Brenner tumor of the ovary with Leydig cell hyperplasia. A histologic and ultrastructural study. Cancer 30: 945–952PubMedCrossRefGoogle Scholar
  181. 178.
    Hammack JE, Kimmel DW, O’Neill BP, et al (1990) Paraneoplastic cerebellar degeneration: A clinical comparison of patients with and without Purkinje cell cytoplasmic antibodies. Mayo Clin Proc 65: 1423–1431PubMedCrossRefGoogle Scholar
  182. 179.
    Hammond D, Winnick S (1974) Paraneoplastic erythrocytosis and ectopic erythropoietins. Ann NY Acad Sci 230: 219–227PubMedCrossRefGoogle Scholar
  183. 180.
    Hamwi GJ, Byron RC, Besch PK, Vorys N, Teteris NJ, Ullery JC (1963) Testosterone synthesis by a Brenner tumor. Part I. Clinical evidence of masculinization during pregnancy. Am J Obstet Gynecol 86: 1015–1020PubMedGoogle Scholar
  184. 181.
    Hart WR, Kumar N, Crissman JD (1980) Ovarian neoplasms resembling sex cord tumors with annular tubules. Cancer 45: 2352–2363PubMedCrossRefGoogle Scholar
  185. 182.
    Hasleton PS, Kelehan P, Whittaker JS, Burslen RW, Turner L (1978) Benign and malignant struma ovarii. Arch Pathol Lab Med 102: 180–184PubMedGoogle Scholar
  186. 183.
    Hayes MC, Scully RE (1987) Ovarian steroid cell tumor (not otherwise specified): A clinicopathological analysis of 63 cases. Am J Surg Pathol 11: 835–845PubMedCrossRefGoogle Scholar
  187. 184.
    Hayes MC, Scully RE (1987) Stromal luteoma of the ovary: A clinico-pathological analysis of 25 cases. Int J Gynecol Pathol 6: 313–321PubMedCrossRefGoogle Scholar
  188. 185.
    Heinonen PK, Koivula T, Pystynen P (1989) Elevated progesterone levels in serum and ovarian venous blood in patients with ovarian tumors. Acta Obstet Gynecol Scand 64: 649–652CrossRefGoogle Scholar
  189. 186.
    Heinonen PK, Koivula T, Rajaniemi H, et al (1986) Peripheral and ovarian venous concentrations of steroid and gonadotropin hormones in postmenopausal women with epithelial ovarian tumors. Gynecol Oncol 25: 1–10PubMedCrossRefGoogle Scholar
  190. 187.
    Henson RA, Urich H (1982) Cancer and the nervous system: The neurological manifestations of systemic malignant disease. Boston, Blackwell Scientific PublicationsGoogle Scholar
  191. 188.
    Herrington JB, Scully RE (1983) Endocrine aspects of germ cell tumors. In: Damjanov I, Knowles B and Solter D (eds) The Human Teratomas. New York, The Humana Press.Google Scholar
  192. 189.
    Herruzo, Redondo E, De Avila IP, et al (1990) Ovarian sex cord tumor with annular tubules and Peutz-Jeghers syndrome. Eur J Gynaecol Oncol 11: 141–144PubMedGoogle Scholar
  193. 190.
    Herve JP, Leroy JP, Gentric-Tilly A, et al (1989) Hypertension arterielle secondaire a une tumeur a renine d’origine ovarienne. Presse Med 18: 2021–2022PubMedGoogle Scholar
  194. 191.
    Hetzel DJ, Stanhope R, O’Neill BP, et al (1990) Gynecologic cancer in patients with subacute cerebellar degeneration predicted by anti-Purkinje cell antibodies and limited in metastatic volume. Mayo Clin Proc 65: 1558–1563PubMedCrossRefGoogle Scholar
  195. 192.
    Heyd J, Livni N, Herbert D, Mor-Yosef S, Glaser B (1989) Gastrin-producing ovarian cystadenocarcinoma: Sensitivity to secretin and SMS 201-995. Gastroenterology 97: 464–467PubMedGoogle Scholar
  196. 193.
    Hoekman K, Tjandra Y, Papapoulos SE (1991) The role of 1,25-dihydroxyvitamin D in the maintenance of hypercalcemia in a patient with an ovarian carcinoma producing parathyroid hormone-related protein. Cancer 68: 642–647PubMedCrossRefGoogle Scholar
  197. 194.
    Holguin T, Padilla RS, Ampuero F (1986) Ovarian adeno-carcinoma presenting with the sign of Leser-Trelat. Gynecol Oncol 25: 128–132PubMedCrossRefGoogle Scholar
  198. 195.
    Holtz G, Johnson TR Jr, Schrock ME (1979) Paraneoplastic hypercalcemia in ovarian tumors. Obstet Gynecol 54: 483–487PubMedGoogle Scholar
  199. 196.
    Hoyt RE, Hamilton JF (1987) Ovarian cancer associated with the nephrotic syndrome. Obstet Gynecol 70: 513–514PubMedGoogle Scholar
  200. 197.
    Hsu C, Ma L, Mak L (1983) Sclerosing stremai tumor of the ovary: Case report and review of the literature. Int J Gynecol Pathol 2: 192–200PubMedCrossRefGoogle Scholar
  201. 198.
    Huang TY, Holaday WJ (1970) An ovarian hilus cell tumor associated with endometrial carcinoma: Report of a case. Am J Clin Pathol 54: 147PubMedGoogle Scholar
  202. 199.
    Hughesdon PE (1958) Thecal and allied reactions in epithelial ovarian tumours. J Obstet Gynaecol Br Commonw 65: 702–709CrossRefGoogle Scholar
  203. 200.
    Hughesdon PE (1983) Lipid cell thecomas of the ovary. Histopathology 7: 681–692PubMedCrossRefGoogle Scholar
  204. 201.
    Hughesdon PE, Fraser IT (1953) Arrhenoblastoma of ovary. Case report and historical review. Acta Obstet Gynecol Scand (suppl 4)32: 1.CrossRefGoogle Scholar
  205. 202.
    Ichinohasama R, Teshima S, Kishi K, et al (1989) Leydig cell tumor of the ovary associated with endometrial carcinoma and containing 17 beta-hydroxysteroid dehydrogenase. Int J Gynecol Pathol 8: 64–71PubMedCrossRefGoogle Scholar
  206. 203.
    Imai A, Furui T, Shimokawa K, Tamaya T (1992) Juvenile granulosa cell tumor in a 2-year-old infant: Report of a case complicated with ascites and acute respiratory distress. Gynecol Oncol 46: 397–400PubMedCrossRefGoogle Scholar
  207. 204.
    Ismail SM, Walker SM (1990) Bilateral virilizing sclerosing stremai tumours of the ovary in a pregnant woman with Gorlin’s syndrome: Implications for pathogenesis of ovarian stremai neoplasms. Histopathology 17: 159–163PubMedCrossRefGoogle Scholar
  208. 205.
    Iturzaeta N, Kenny FM, Sieber W (1967) Precocious pseudopuberty due to granulosa cell tumor in three girls. Am J Dis Child 114: 39Google Scholar
  209. 206.
    Jackson B, Valentine R, Wagner G (1986) Primary aldosteronism due to a malignant ovarian tumour. Aust NZ J Med 16: 69–71CrossRefGoogle Scholar
  210. 207.
    Jacobs AJ, Deppe G, Cohen CJ (1982) Combination chemotherapy of ovarian granulosa cell tumor with CIS-platinum and doxorubicin. Gynecol Oncol 14: 294PubMedCrossRefGoogle Scholar
  211. 208.
    Jarabak J, Talerman A (1983) Virilization due to a metastasizing granulosa cell tumor. Int J Gynecol Pathol 2: 316–324PubMedCrossRefGoogle Scholar
  212. 209.
    Jeppsson S, Karlsson S, Kuliander S (1986) Gonadal steroids, gonadotropins and endometrial histology in postmenopausal women with malignant ovarian tumors. Acta Obstet Gynecol Scand 65: 207–210PubMedCrossRefGoogle Scholar
  213. 210.
    Johnson AD, Herbert AA, Esterly NB (1986) Nevoid basal cell carcinoma syndrome. Bilateral ovarian fibromas in a 3½rld girl. J Am Acad Dermatol 14: 371–374PubMedCrossRefGoogle Scholar
  214. 211.
    Johnston WW, Goldston WR, Montgomery MS (1971) Clinicopathologic studies in feminizing tumors of the ovary. III. The role of genital cytology. Acta Cytol 15: 334PubMedGoogle Scholar
  215. 212.
    Jolies CJ, Beeson JH, Abbott T (1985) Progesterone production in adenocarcinoma of the colon metastatic to the ovaries. Obstet Gynecol 65: 853–857Google Scholar
  216. 213.
    Jolly H (1955) Sexual Precocity. A personal study of 69 patients. American Lecture Series, Springfield, IL, Charles Thomas.Google Scholar
  217. 214.
    Jorgensen EO, Dockerty MB, Wilson RB (1970) Clinicopathologic study of 53 cases of Brenner tumors of the ovary. Am J Obstet Gynecol 108: 122–127PubMedGoogle Scholar
  218. 215.
    Josse RG, Wilson DR, Heersche JNM, Mills JRF, Murray TM (1981) Hypercalcemia with ovarian carcinoma: Evidence of a pathogenetic role for prostaglandins. Cancer 48: 1233–1241PubMedCrossRefGoogle Scholar
  219. 216.
    Judd HL, Spore WW, Talner LB, Rigg LA, Yen SSC, Benirschke K (1974) Preoperative localization of a testosterone-secreting ovarian tumor by retrograde venous catheterization and selective sampling. Am J Obstet Gynecol 120: 91PubMedGoogle Scholar
  220. 217.
    Julkunen R, Partanen S, Salaspuro M (1983) Gastrin-producing ovarian mucinous cystadenoma. J Clin Gastroenterol 5: 67–70PubMedCrossRefGoogle Scholar
  221. 218.
    Junaid TA, Nkposong EO, Kolawole TM (1972) Cutaneous meningiomas and an ovarian fibroma in a 3-year-old girl. J Pathol 108: 165PubMedCrossRefGoogle Scholar
  222. 219.
    Kalavathi N (1971) Granulosa cell tumor—hormonal aspects and radiosensitivity. Clin Radiol 22: 524–527PubMedCrossRefGoogle Scholar
  223. 220.
    Kallenberg GA, Pesce CM, Norman B, Ratner RE, Silverberg SG (1990) Ectopic hyperprolactinemia resulting from an ovarian teratoma. JAMA 263: 2472–2474PubMedCrossRefGoogle Scholar
  224. 221.
    Kaplan C, Hawley R (1981) Dysgerminoma with giant cells. A case report with immunoperoxidase. Diagn Gynecol Obstet 3/4: 325–329.PubMedGoogle Scholar
  225. 222.
    Katsube Y, Berg JM, Silverberg SG (1982) Epidemiologic pathology of ovarian tumors: A histopathologic review of primary ovarian neoplasms dia area, 1 July–31 December 1969 and 1 July–31 December 1979. Int J Gynecol Pathol 1: 3–16PubMedCrossRefGoogle Scholar
  226. 223.
    Katsube Y, Iwaoki Y, Silverberg SG, Fujiwara A (1988) Sclerosing stremai tumor of the ovary associated with endometrial adenocarcinoma. A case report. Gynecol Oncol 29: 392–398PubMedCrossRefGoogle Scholar
  227. 224.
    Kempers RD, Dockerty MB, Hoffman DL, et al (1970) Struma ovarii—ascitic, hyperthyroid, and asymptomatic syndromes. Ann Intern Med 72: 883–893PubMedGoogle Scholar
  228. 225.
    Kempson RL (1968) Ultrastructure of ovarian stremai cell tumors. Sertoli-Leydig cell tumor and lipid cell tumor. Arch Pathol 86: 492PubMedGoogle Scholar
  229. 226.
    Khalifa MA, Sesterhenn IA (1990) Tumor markers of epithelial ovarian neoplasms. Int J Gynecol Pathol 9: 217–230PubMedCrossRefGoogle Scholar
  230. 227.
    Kim I, Young RH, Scully RE (1985) Leydig cell tumors of the testis. A clinicopathological analysis of 40 cases and review of the literature. Am J Surg Pathol 9: 177–192PubMedCrossRefGoogle Scholar
  231. 228.
    Kobayashi M, Hamada H, Yamoto M, et al (1990) Ovarian clear-cell carcinoma producing estradiol and human chorionic gonadotropin. Acta Obstet Gynecol Scand 69: 183–185PubMedCrossRefGoogle Scholar
  232. 229.
    Konishi I, Fujii S, Ishikawa Y, Suzuki A, Okamura H, Mori T (1986) Ovarian fibroma with Leydig cell hyperplasia of the adjacent strema: A light and electron microscopic study. Int J Gynecol Pathol 5: 170–178PubMedGoogle Scholar
  233. 230.
    Korzets A, Nouriel H, Steiner Z, et al (1986) Resistant hypertension associated with a renin-producing ovarian Sertoli cell tumor. Am J Clin Pathol 85: 242–247PubMedGoogle Scholar
  234. 231.
    Kottmeier HL (1953) Carcinoma of the Female Genitalia. The Abraham Flexner Lectures, Series No. 11, Baltimore, Williams and Wilkins.Google Scholar
  235. 232.
    Kraemer BB, Silva EG, Sneige N (1984) Fibrosarcoma of the ovary. A new component in the nevoid basal-cell carcinoma syndrome. Am J Surg Pathol 8: 231–236PubMedCrossRefGoogle Scholar
  236. 233.
    Kuhnel R, Rao BR, Stolk JG, van Kessel H, Seldernrijk CA, Willig AP (1987) Estrogen synthesizing rare malignant Brenner tumor of the ovary with the presence of progesterone and androgen receptors in the absence of estrogen receptors. Gynecol Oncol 26: 263–269PubMedCrossRefGoogle Scholar
  237. 234.
    Kulkarni JN, Mistry RC, Kamat MR, Chinoy R, Lotlikar RG (1990) Autonomous aldosterone-secreting ovarian tumor. Gynecol Oncol 37: 284–289PubMedCrossRefGoogle Scholar
  238. 235.
    Kung AWC, Ma JTC, Wang C, et al (1990) Hyperthyroidism during pregnancy due to coexistence of struma ovarii and Graves’ disease. Postgrad Med J 66: 132–133PubMedCrossRefGoogle Scholar
  239. 236.
    Kurman RJ, Andrade D, Goebelsmann U, Taylor CR (1978) An immunohistochemical study of steroid localization in Sertoli-Leydig tumors of the ovary and testis. Cancer 42: 1772PubMedCrossRefGoogle Scholar
  240. 237.
    Kurman RJ, Ganjei P, Nadjii M (1984) Contributions of immunocytochemistry to the diagnosis and study of ovarian neoplasms. Int J Gynecol Pathol 3: 3–26PubMedCrossRefGoogle Scholar
  241. 238.
    Kurman RJ, Goebelsmann U, Taylor CR (1979) Steroid localization in granulosa-theca tumors of the ovary. Cancer 43: 2377PubMedCrossRefGoogle Scholar
  242. 239.
    Kurman RJ, Noms HJ (1976) Malignant mixed germ cell tumors of the ovary. Obstet Gynecol 48: 579–589PubMedGoogle Scholar
  243. 240.
    Kurman RJ, Noms HJ (1976) Embryonal cell carcinoma of the ovary. A clinicopathologic entity distinct from endodermal sinus tumor resembling embryonal carcinoma of the adult testis. Cancer 38: 2420–2433PubMedCrossRefGoogle Scholar
  244. 241.
    Kuzma JF, King JM (1948) Dyschondroplasia with hemangiomatosis (Maffucci’s syndrome) and teratoid tumor of the ovary. Arch Pathol 46: 74Google Scholar
  245. 242.
    Lack EE, Perez-Atayde AR, Murthy ASK, Goldstein DP, Crigler JF, Vawter GF (1981) Granulosa theca cell tumors in premenarchal girls. A clinical and pathologic study of ten cases. Cancer 48: 1846PubMedCrossRefGoogle Scholar
  246. 243.
    Lawhead RA, Copeland LJ, Edwards CL (1985) Bilateral ovarian hemangiomas associated with diffuse abdominopelvic hemangiomatosis. Obstet Gynecol 65: 597–599PubMedGoogle Scholar
  247. 244.
    Lee JC, Yamauchi H, Hopper J Jr (1966) The association of cancer and the nephrotic syndrome. Ann Intern Med 64: 41–57PubMedGoogle Scholar
  248. 245.
    Lewis RJ, Ketcham AS (1973) Maffucci’s syndrome: Functional and neoplastic significance. Case report and review of the literature. J Bone Joint Surg 55-A: 1465.PubMedGoogle Scholar
  249. 246.
    Listrom WB, Foucar CE (1990) Letter to the Editor. Am J Clin Pathol 94: 803–804PubMedGoogle Scholar
  250. 247.
    Long TT, Barton TK, Draffin R, Reeves WJ, McCarty KS (1980) Conservative management of the Zollinger-Ellison syndrome. Ectopic gastrin production by an ovarian cystadenoma. JAMA 243: 1837–1839PubMedCrossRefGoogle Scholar
  251. 248.
    Lusch CJ, Mercurio TM, Runyeon WK (1978) Delayed recurrence and chemotherapy of a granulosa cell tumor. Obstet Gynecol 51: 505PubMedCrossRefGoogle Scholar
  252. 249.
    Lyday RO (1952) Fibroma of the ovary with abdominal implants. Am J Surg 84: 737PubMedCrossRefGoogle Scholar
  253. 250.
    MacAulay MA, Weliky I, Schulz RA (1967) Ultrastructure of a biosynthetically active granulosa cell tumor. Lab Invest 17: 562–570PubMedGoogle Scholar
  254. 251.
    MacKenzie AH, Scherbel AL (1963) Connective tissue syndromes associated with carcinoma. Geriatrics 18: 745–753PubMedGoogle Scholar
  255. 252.
    Mahlck C, Backstrom T, Kjellgren O (1986) Androstenedione production by malignant epithelial ovarian tumors. Gynecol Oncol 25: 217–222PubMedCrossRefGoogle Scholar
  256. 253.
    Mahlck C, Backström T, Kjellgren O (1988) Plasma level of estradiol in patients with ovarian malignant tumors. Gynecol Oncol 30: 313–320PubMedCrossRefGoogle Scholar
  257. 254.
    Mahlck C-G, Grankvist K, Kjellgren O, Backstrom T (1990) Human chorionic gonadotropin, follicle-stimulating hormone, and luteinizing hormone in patients with epithelial ovarian carcinoma. Gynecol Oncol 36: 219–225PubMedCrossRefGoogle Scholar
  258. 255.
    Malfetano JH, Degnan E, Florentin R (1990) Para-endocrine hypercalcemia and ovarian small cell carcinoma. NY State J Med 90: 206–207Google Scholar
  259. 256.
    Malkasian GD Jr, Webb MJ, Jorgensen EO (1974) Observations on chemotherapy of granulosa cell carcinomas and malignant ovarian teratomas. Obstet Gynecol 44: 885PubMedGoogle Scholar
  260. 257.
    Mann WJ, Chumas J, Rosenwaks Z, Merrill JA, Davenport D (1986) Elevated serum alpha-fetoprotein associated with Sertoli-Leydig cell tumors of the ovary. Obstet Gynecol 67: 141–144PubMedGoogle Scholar
  261. 258.
    March DE, Desai AG, Park CH, et al (1988) Struma ovarii: Hyperthyroidism in a postmenopausal woman. J Nucl Med 29: 263–265PubMedGoogle Scholar
  262. 259.
    Marcus CC, Marcus SL (1961) Struma ovarii. A report of 7 cases and a review of the subject. Am J Obstet Gynecol 81: 752–762PubMedGoogle Scholar
  263. 260.
    Margolin KA, Pak HY, Esensten ML, Doroshow JH (1985) Hepatic metastasis in granulosa cell tumor of the ovary. Cancer 56: 691–695PubMedCrossRefGoogle Scholar
  264. 261.
    Marieb HJ, Spangler S, Kashgarian M, Heiman A, Schwartz ML, Schwartz PE (1983) Cushing’s syndrome secondary to ectopic cortisol production by an ovarian car-cinoma. J Clin Endocrinol Metab 57: 737–740PubMedCrossRefGoogle Scholar
  265. 262.
    Martinelli G, Govoni E, Pileri S, Grigioni FW, Doglioni C, Pelusi G (1983) Sclerosing stromal tumor of the ovary. Virchows Arch (Pathol Anat) 402: 155–161CrossRefGoogle Scholar
  266. 263.
    Matias-Guiu X, Prat J (1990) Ovarian tumors with functioning stroma. An immunohistochemical study of 100 cases with human chorionic gonadotropin monoclonal and polyclonal antibodies. Cancer 65: 2001–2005PubMedCrossRefGoogle Scholar
  267. 264.
    Matson PN, Mackem SM, Norton JA, Gardner JD, O’Dorisio TM, Jensen RT (1989) Ovarian carcinoma as a cause of Zollinger-Ellison syndrome. Natural history, secretory products, and response to provocative tests. Gastroenterology 97: 468–471Google Scholar
  268. 265.
    McGowan L, Young RH, Scully RE (1980) Peutz-Jeghers syndrome with adenoma malignum of cervix. A report of two cases. Gynecol Oncol 10: 125PubMedCrossRefGoogle Scholar
  269. 266.
    McKay DG, Hertig AT, Hickey WF (1953) The histogenesis of granulosa and theca tumors of the human ovary. Obstet Gynecol 1: 125–136PubMedGoogle Scholar
  270. 267.
    McKay DG, Robinson D, Hertig AT (1949) Histochemical observations on granulosa cell tumors, thecomas, and fibromas of the ovary. Am J Obstet Gynecol 58: 625–639PubMedGoogle Scholar
  271. 268.
    McLellan R, Currie JL, Royal W, et al (1988) Ovarian carcinoma and paraneoplastic cerebellar degeneration. Obstet Gynecol 72: 922–924PubMedGoogle Scholar
  272. 269.
    McMahon JT, Hart WR (1988) Ultrastructural analysis of small cell carcinomas of the ovary. Am J Clin Pathol 90: 523–529PubMedGoogle Scholar
  273. 270.
    McNulty JR (1959) The ovarian serous cystadenofibroma. A report of 25 cases. Am J Obstet Gynecol 77: 1338–1344PubMedGoogle Scholar
  274. 271.
    Medsger TA, Dixon JA, Garwood VF (1982) Palmar fasciitis and polyarthritis associated with ovarian carcinoma. Ann Intern Med 96: 424–431PubMedGoogle Scholar
  275. 272.
    Meigs JV (1954) Fibroma of the ovary with ascites and hydrothorax. Meigs’ syndrome. Am J Obstet Gynecol 67: 962PubMedGoogle Scholar
  276. 273.
    Meiling RL, Bouselis JG, Teteris NJ, Ullery JC, George OT (1963) Histochemical observations of a Brenner cell tumor with masculinization. Am J Obstet Gynecol 87: 463–470PubMedGoogle Scholar
  277. 274.
    Miettinen M, Talerman A, Wahlström T, Astengo-Osuna C, Virtanen I (1988) Cellular differentiation in ovarian sex-cord-stromal and germ-cell tumors studied with antibodies to intermediate filament proteins. Am J Surg Pathol 9: 640–651CrossRefGoogle Scholar
  278. 275.
    Meyer-Hofmann G, Schwarzkopf H, Hartmann H (1960) Spontaneous hypoglycemia with extrapancreatic tumors. Dtsch Med Wochenschr 85: 2106–2108PubMedCrossRefGoogle Scholar
  279. 276.
    Michael CA (1967) Pelvic fibroma causing recurrent attacks of hypoglycemia. J Obstet Gynaecol Br Commow 74: 301–303CrossRefGoogle Scholar
  280. 277.
    Miettinen M, Lehto V-P, Virtanen I (1983) Expression of intermediate filaments in normal ovaries and ovarian epithelial, sex cord-stromal, and germinal tumors. Int J Gynecol Pathol 2: 64–71PubMedCrossRefGoogle Scholar
  281. 278.
    Miettinen M, Talerman A, Wahlstrom T, Astengo-Osuna C, Virtanen I (1985) Cellular differentiation in ovarian sex-cord—stromal and germ-cell tumors studied with antibodies to intermediate-filament proteins. Am J Surg Pathol 9: 640–651PubMedCrossRefGoogle Scholar
  282. 279.
    Mittal KR, Blechman A, Greco MA, Alfonso F, Demopoulos R (1992) Lymphoma of ovary with stromal luteinization, presenting as secondary amenorrhea. Gynecol Oncol 45: 69–75PubMedCrossRefGoogle Scholar
  283. 280.
    Miyauchi J, Yamazaki K, Kiso I, et al (1987) Bilateral ovarian hemangiomas associated with diffuse hemangio-endotheliomatosis: A case report. Acta Pathol Jpn 37: 1347–1355PubMedGoogle Scholar
  284. 281.
    Mohabeer J, Buckley CH, Fox H (1983) An immunohis-tochemical study of the incidence and significance of human chorionic gonadotrophin synthesis by epithelial ovarian neoplasms. Gynecol Oncol 16: 78–84PubMedCrossRefGoogle Scholar
  285. 282.
    Montag TW, Murphy RE, Belinson JL (1984) Virilizing malignant lipid cell tumor producing erythropoietin. Gynecol Oncol 19: 98–103PubMedCrossRefGoogle Scholar
  286. 283.
    Mordel N, Margalioth EJ, Harats N, et al (1988) Concurrence of ovarian cancer and dermatomyositis. A report of two cases and literature review. J Reprod Med 33: 649–655PubMedGoogle Scholar
  287. 284.
    Morgan DR, Wells M, MacDonald RC, Johnston D (1985) Zollinger-Ellison syndrome due to a gastrin secreting ovarian mucinous cystadenoma. Case report. Br J Obstet Gynaecol 92: 867–869PubMedCrossRefGoogle Scholar
  288. 285.
    Morgello S, Schwartz E, Horwith M, et al (1988) Ectopic insulin production by a primary ovarian carcinoid. Cancer 61: 800–805PubMedCrossRefGoogle Scholar
  289. 286.
    Morris J McL, Scully RE (1958) Endocrine Pathology of the Ovary. St. Louis, C.V. Mosby Co.Google Scholar
  290. 287.
    Morrison CW, Woodruff JD (1964) Fibrothecoma and associated ovarian stromal neoplasia. Obstet Gynecol 23: 344PubMedGoogle Scholar
  291. 288.
    Motlik K (1966) An estrogen-producing “yellow tumour” of the ovary associated with arterial hypertension. Endokrynol Pol 17: 525–539PubMedGoogle Scholar
  292. 289.
    Motlik K, Abrahamova J, Koutecky J, Horejsi J, Starka L (1987) Successive bilateral arrhenoblastoma. Path Res Pract 182: 453–584CrossRefGoogle Scholar
  293. 290.
    Motlik K, Starka L (1973) Adrenocortical tumour of the ovary. (A case report with particular stress upon morphological and biochemical findings.) Neoplasma 20: 97PubMedGoogle Scholar
  294. 291.
    Motlik K, Stejskalova A, Stejskal J, Kobilkova J, Starka L (1988) Hilus cell tumors of the ovary. Cesk Pathol 24: 144–160Google Scholar
  295. 292.
    Nakashima N, Young RH, Scully RE (1984) Androgenic granulosa cell tumors of the ovary. A clinicopathological analysis of seventeen cases and review of the literature. Arch Pathol Lab Med 108: 786PubMedGoogle Scholar
  296. 293.
    Napoli VM, Wallach H (1976) Pancytopenia associated with a granulosa-cell tumor of the ovary. Report of a case. Am J Clin Pathol 65: 344–350PubMedGoogle Scholar
  297. 294.
    Neubecker RD, Breen JL (1962) Gynandroblastoma. A report of five cases with a discussion of the histogenesis and classification of ovarian tumors. Am J Clin Pathol 38: 60PubMedGoogle Scholar
  298. 295.
    Neville AJ, Gilchrist KW, Davis TE (1984) The chemotherapy of granulosa cell tumors of the ovary: Experience of the Wisconsin Clinical Cancer Center. Med Pediatr Oncol 12: 397–400PubMedCrossRefGoogle Scholar
  299. 296.
    Nguyen KQ, Hurst CG, Pierson DL, et al (1983) Sweet’s syndrome and ovarian carcinoma. Cutis 32: 152–154PubMedGoogle Scholar
  300. 297.
    Nichols J, Warren JC, Mantz FA (1962) ACTH-like excretion from carcinoma of the ovary. JAMA 182: 713–718PubMedCrossRefGoogle Scholar
  301. 298.
    Nieminen U, Von Numers C, Widholm O (1963) Struma ovarii. Acta Obstet Gynecol Scand 42: 399–424CrossRefGoogle Scholar
  302. 299.
    Niswander KR, Courey NG, Woodward T (1965) Precocious pseudopuberty caused by ovarian tumors. Obstet Gynecol 26: 381PubMedGoogle Scholar
  303. 300.
    Nogales FF, Concha A, Plata C, Ruiz-Avila I (1993) Granulosa cell tumor of the ovary with diffuse true hepatic differentiation simulating stromal luteinization. Am J Surg Pathol 17: 85–90PubMedCrossRefGoogle Scholar
  304. 301.
    Noms HJ, Taylor HB (1968) Prognosis of granulosa-theca tumors of the ovary. Cancer 21: 255CrossRefGoogle Scholar
  305. 302.
    Noms HJ, Taylor HB (1969) Virilization associated with cystic granulosa tumors. Obstet Gynecol 34: 629Google Scholar
  306. 303.
    Novak DJ, Lauchlan SC, McCawley JC, Faiman C (1970) Virilization during pregnancy. Case report and review of literature. Am J Med 49: 281–290PubMedCrossRefGoogle Scholar
  307. 304.
    Novak ER (1967) Gynandroblastoma of the ovary. Review of 8 cases from the Ovarian Tumor Registry. Obstet Gynecol 30: 709PubMedGoogle Scholar
  308. 305.
    Novak ER, Kutchmeshgi J, Mupas RS, Woodruff JD, et al (1971) Feminizing gonadal stremai tumors. Obstet Gynecol 38: 701PubMedGoogle Scholar
  309. 306.
    Novak ER, Long JH (1965) Arrhenoblastoma of the ovary. A review of the Ovarian Tumor Registry. Am J Obstet Gynecol 92: 1082PubMedGoogle Scholar
  310. 307.
    Novak ER, Mattingly RF (1960) Hilus cell tumor of the ovary. Obstet Gynecol 15: 425PubMedGoogle Scholar
  311. 308.
    Nussbaum SR, Gas R, Arnold A (1990) Hypercalcemia and ectopic secretion of parathyroid hormone by an ovarian carcinoma with rearrangement of the gene for parathyroid hormone. N Engl J Med 323: 1324–1328PubMedCrossRefGoogle Scholar
  312. 309.
    Ober WB, Pollak A, Gerstmann KE, Kupperman HS (1962) Krukenberg tumor with androgenic and progestational activity. Am J Obstet Gynecol 84: 739–744PubMedGoogle Scholar
  313. 310.
    O’Hern TM, Neubecker RD (1962) Arrhenoblastoma. Obstet Gynecol 19: 758PubMedGoogle Scholar
  314. 311.
    Okolo SO, Darley C, Melville HAH, Kirkham N (1990) Virilizing ovarian serous cystadenoma. Case report. Br J Obstet Gynecol 97: 269–271CrossRefGoogle Scholar
  315. 312.
    O’Neill RT, Mikuta JJ (1970) Hypoglycemia associated with serous cystadenocarcinoma of the ovary. Obstet Gynecol 35: 287–289PubMedGoogle Scholar
  316. 313.
    Osborn RH, Yannone ME (1971) Plasma androgens in the normal and androgenic female. A review. Obstet Gynecol Surv 26: 195CrossRefGoogle Scholar
  317. 314.
    Palmer PE, Bogojavlensky S, Bhan AK, Scully RE (1990) Prolactinoma in wall of ovarian dermoid cyst with hyper-prolactinemia. Obstet Gynecol 75: 540–543PubMedGoogle Scholar
  318. 315.
    Paoletti M, Pridjian G, Okagaki T, Talerman A (1987) A stremai Leydig cell tumor of the ovary occurring in a pregnant 15-year-old girl. Ultrastructural findings. Cancer 60: 2806–2810PubMedCrossRefGoogle Scholar
  319. 316.
    Plotz EJ, Wiener M, Stein AA (1966) Steroid synthesis in cystadenocarcinoma of the ovaries. Am J Obstet Gynecol 94: 189–194PubMedGoogle Scholar
  320. 317.
    Paraskevas M, Scully RE (1989) Hilus cell tumor of the ovary. A clinicopathological analysis of 12 Reinke crystal-positive and 9 crystal-negative cases. Int J Gynecol Pathol 8: 299–310PubMedCrossRefGoogle Scholar
  321. 318.
    Parish JM, Lufkin EG, Lee RA, Gaffey TA (1984) Ovarian leiomyoma with hilus cell hyperplasia that caused virilization. Mayo Clinic Proc 59: 275–277CrossRefGoogle Scholar
  322. 319.
    Parsons V, Rigby R (1958) Cushing’s syndrome associated with adenocarcinoma of the ovary. Lancet 2: 992–994PubMedCrossRefGoogle Scholar
  323. 320.
    Payne D, Muss HB, Homesley HD, Jobson VW, Baird FG (1981) Autoimmune hemolytic anemia and ovarian dermoid cysts: Case report and review of the literature. Cancer 48: 721–724PubMedCrossRefGoogle Scholar
  324. 321.
    Pogliani EM, Fowst C, Maffe P, et al (1988) CNS metastasis in ovarian cancer with microangiopathic hemolytic anemia associated with diffuse intravascular coagulation. Tumor 74: 731–736Google Scholar
  325. 322.
    Post WD, Steele HD, Gorwill RH (1978) Mucinous cystadenoma and virilization during pregnancy. Can Med Assoc J 118: 952–953Google Scholar
  326. 323.
    Prat J, Bhan AK, Dickersin GR, Robboy SJ, Scully RE (1982) Hepatoid yolk sac tumor of the ovary (endodermal sinus tumor with hepatoid differentiation). A light microscopic, ultrastructural and immunohistochemical study of seven cases. Cancer 50: 2355–2368PubMedCrossRefGoogle Scholar
  327. 324.
    Prat J, Scully RE (1981) Cellular fibromas and fibrosarcomas of the ovary: A comparative clinicopathologic analysis of seventeen cases. Cancer 47: 2663PubMedCrossRefGoogle Scholar
  328. 325.
    Prat J, Young RH, Scully RE (1982) Ovarian Sertoli-Leydig cell tumors with heterologous elements, (ii) cartilage and skeletal muscle: A clinicopathologic analysis of twelve cases. Cancer 50: 2465PubMedCrossRefGoogle Scholar
  329. 326.
    Price A, Russell P, Elliott P, Bannatyne P (1990) Composite mucinous and granulosa-cell tumor of ovary: Case report of a unique neoplasm. Int J Gynecol Pathol 9: 372–378PubMedCrossRefGoogle Scholar
  330. 327.
    Primrose JN, Maloney M, Wells M, Bulgim O, Johnston D (1988) Gastrin-producing ovarian mucinous cystadenomas: A cause of the Zollinger-Ellison syndrome. Surgery 104: 830–833PubMedGoogle Scholar
  331. 328.
    Pruett KM, Gordon AN, Estrada R, et al (1988) Small-cell carcinoma of the ovary: An aggressive epithelial cancer occurring in young patients. Gynecol Oncol 29: 365–369PubMedCrossRefGoogle Scholar
  332. 329.
    Prunty FTG. (1967) Hirsutism, virilism and apparent virilism and their gonadal relationship. Part I. J Endocrinol 38: 85PubMedCrossRefGoogle Scholar
  333. 330.
    Pysher TJ, Hitch DC, Krous HF (1981) Bilateral juvenile granulosa cell tumors in a 4-month ody dysmorphic infant. A clinical, histologic, and ultrastructural study. Am J Surg Pathol 5: 789PubMedCrossRefGoogle Scholar
  334. 331.
    Quinn MA, Oster AO, Fortune D, Hudson B (1981) Sclerosing stremai tumor of the ovary. Case report with endocrine studies. Br J Obstet Gynaecol 88: 555–558PubMedCrossRefGoogle Scholar
  335. 332.
    Raggio M, Kaplan AL, Harberg JF (1983) Recurrent ovarian fibromas with basal cell nevus syndrome (Gorlin syndrome). Obstet Gynecol 61: 95s–96sPubMedGoogle Scholar
  336. 333.
    Ramzy I (1976) Signet-ring stremai tumor of ovary. Histochemical, light, and electron microscopic study. Cancer 38: 166–172PubMedCrossRefGoogle Scholar
  337. 334.
    Reddick RL, Walton LA (1982) Sertoli-Leydig cell tumor of the ovary with teratomatous differentiation. Cancer 50: 1171–1176PubMedCrossRefGoogle Scholar
  338. 335.
    Robboy SJ, Noms HJ, Scully RE (1975) Insular carcinoid primary in the ovary. A clinicopathologic analysis of 48 cases. Cancer 36: 404–418PubMedCrossRefGoogle Scholar
  339. 336.
    Robboy SJ, Scully RE (1980) Strumal carcinoid of the ovary. Cancer 46: 2019–2034PubMedCrossRefGoogle Scholar
  340. 337.
    Robboy SJ, Scully RE, Norris HJ (1977) Primary trabecular carcinoid of the ovary. Obstet Gynecol 49: 202–207PubMedGoogle Scholar
  341. 338.
    Robboy SJ, Scully RE, Norris HJ (1974) Carcinoid metastatic to the ovary. A clinicopathologic analysis of 35 cases. Cancer 33: 798–811PubMedCrossRefGoogle Scholar
  342. 339.
    Robinson B, Eckstein R, Stiel JN, Payne WH, Kemp J (1988) An ovarian cyst associated with virilization. Aust NZ J Med 18: 161–163CrossRefGoogle Scholar
  343. 340.
    Rome RM, Fortune DW, Quinn MA, Brown JB (1981) Functioning ovarian tumors in postmenopausal women. Obstet Gynecol 57: 705–710PubMedGoogle Scholar
  344. 341.
    Rome RM, Laverty CR, Brown JB (1973) Ovarian tumours in postmenopausal women. Clinicopathological features and hormonal studies. J Obstet Gynaecol Br Commonw 80: 984–991PubMedCrossRefGoogle Scholar
  345. 342.
    Roth LM, Anderson MC, Govan ADT, Langley FA, Gowing NFC, Woodcock AS (1981) Sertoli-Leydig cell tumors. A cliniclpathologic study of 34 cases. Cancer 48: 187PubMedCrossRefGoogle Scholar
  346. 343.
    Roth LM, liban E, Czernobilsky B (1982) Ovarian endometrioid tumors mimicking Sertoli and Sertoli-Leydig cell tumors. Sertoliform variant of endometrioid carcinoma. Cancer 50: 1322PubMedCrossRefGoogle Scholar
  347. 344.
    Roth LM, Nicholas TR, Ehrlich CE (1979) Juvenile granulosa cell tumor. A clinicopathologic study of three cases with ultrastructural observations. Cancer 44: 2194PubMedCrossRefGoogle Scholar
  348. 345.
    Roth LM, Slayton RE, Brady LW, Blesdsing JA, Johnson G (1985) Retiform differentiation in ovarian Sertoli-Leydig cell tumors. A clinicopathologic study of six cases from a gynecologic oncology study group. Cancer 55: 1093PubMedCrossRefGoogle Scholar
  349. 346.
    Roth LM, Sternberg WH (1973) Ovarian stromal tumors containing Leydig cells. II. Pure Leydig cell tumor, nonhilar type. Cancer 32: 952PubMedCrossRefGoogle Scholar
  350. 347.
    Roth LM, Sternberg WH (1983) Partly luteinized theca cell tumor of the ovary. Cancer 51: 1697PubMedCrossRefGoogle Scholar
  351. 348.
    Rubin DK, Frost JF (1963) The cytologic detection of ovarian cancer. Acta Cytol 7: 191–195PubMedGoogle Scholar
  352. 349.
    Rutgers J, Scully RE (1986) Functioning ovarian tumors with peripheral steroid cell proliferation: A report of twenty-four cases. Int J Gynecol Pathol 5: 319–337PubMedCrossRefGoogle Scholar
  353. 350.
    Ryan DE, Burkes EJ Jr (1973) The multiple basalcell nevus syndrome in a Negro family. Oral Surg 36: 831–840PubMedCrossRefGoogle Scholar
  354. 351.
    Sack GH, Levin J, Bell WR (1977) Trousseau’s syndrome and other manifestations of chronic disseminated coagulopathy in patients with neoplasms: Clinical, pathophysiologic and therapeutic features. Medicine 56: 1–37PubMedGoogle Scholar
  355. 352.
    Saitoh A, Tsutsumi Y, Osamura RY, Watanabe K (1989) Sclerosing stromal tumor of the ovary. Immunohistochemical and electron-microscopic demonstration of smoothmuscle differentiation. Arch Pathol Lab Med 113: 372–376PubMedGoogle Scholar
  356. 353.
    Salm R (1967) Pure and mixed hilus cell tumors of ovary. Ann Roy Coll Surg Engl 41: 344Google Scholar
  357. 354.
    Salm R (1974) Ovarian hilus-cell tumors: their varying presentations. J Pathol 113: 117PubMedCrossRefGoogle Scholar
  358. 355.
    Salomon-Bernard Y, Thibaud E, Vignai J, Musset R (1975) Tumeurs a Stroma Fonctionnel. In: Cabanne F (ed) Tumeurs de l’ovaire, Chapter IL Paris, Masson et Cie, pp 309.Google Scholar
  359. 356.
    Samaan NA, Smith JP, Rutledge FN, Schultz PN (1976) The significance of measurement of human placental lactogen, human chorionic gonadotropin, and carcinoembryonic antigen in patients with ovarian carcinoma. Am J Obstet Gynecol 126: 186–189PubMedGoogle Scholar
  360. 357.
    Samanth KK, Black WC (1970) Benign ovarian stromal tumors associated with free peritoneal fluid. Am J Obstet Gynecol 107: 538PubMedGoogle Scholar
  361. 358.
    Sasano H, Sasano N (1989) What’s new in the localization of sex steroids in the human ovary and its tumors? Pathol Res Pract 185: 942–948PubMedCrossRefGoogle Scholar
  362. 359.
    Sasano H, Okamoto M, Mason JI, et al (1989) Immunohis-tochemical studies of steroidogenic enzymes (aromatase, 17-hydroxylase and cholesterol side-chain cleavage cy-tochromes P-450) in sex cord-stromal tumors of the ovary. Hum Pathol 20: 452–457PubMedCrossRefGoogle Scholar
  363. 360.
    Scaling ST, Kaufman RH, Patten BM (1979) Dermatomyositis and female malignancy. Obstet Gynecol 54: 474–477PubMedGoogle Scholar
  364. 361.
    Schnoy N (1982) Ultrastructure of a virilizing ovarian Leydig-cell tumor. Virchows Arch (Pathol Anat) 397: 17CrossRefGoogle Scholar
  365. 362.
    Schwartz PE, Smith JP (1976) Treatment of ovarian stromal tumors. Am J Obstet Gynecol 125: 402PubMedGoogle Scholar
  366. 363.
    Scully RE (1953) An unusual ovarian tumor containing Leydig cells but associated with endometrial hyperplasia, in a postmenopausal woman. J Clin Endocrinol Metab 13: 1254–1263PubMedCrossRefGoogle Scholar
  367. 364.
    Scully RE (1962) Androgenic lesions of the ovary. In: Grady HG, Smith DE (eds) The Ovary, Chapter 9, International Academy of Pathology Monograph No. 3. Baltimore, Williams and Wilkins, pp 143.Google Scholar
  368. 365.
    Scully RE (1964) Stromal luteoma of the ovary. A distinctive type of lipoid-cell tumor. Cancer 17: 769PubMedCrossRefGoogle Scholar
  369. 366.
    Scully RE (1968) Sex cord-mesenchyme tumours. Pathologic classification and its relation to prognosis and treatment. In: Junqueira, AC, Gentil F (eds) Ovarian Cancer, IUCC Monograph Series, Vol IL Heidelberg, Springer-Verlag, pp 40–56.CrossRefGoogle Scholar
  370. 367.
    Scully RE (1970) Sex cord tumor with annular tubules. A distinctive ovarian tumor of the Peutz-Jeghers syndrome. Cancer 25: 1107PubMedCrossRefGoogle Scholar
  371. 368.
    Scully RE (1970) Gonadoblastoma. A review of 74 cases. Cancer 25: 1340PubMedCrossRefGoogle Scholar
  372. 369.
    Scully RE (1979) Tumors of the Ovary and Maldeveloped Gonads. In Atlas of Tumor Pathology, 2nd series, Fascicle No. 16, Armed Forces Institute of Pathology, Washington DC.Google Scholar
  373. 370.
    Scully RE (1987) Ovarian tumors with functioning stroma. In: Fox H (ed) Haines and Taylor’s Gynaecological and Obstetrical Pathology, 3rd ed. Edinburgh, Churchill Liv-ingstone, pp 724–736.Google Scholar
  374. 371.
    Scully RE, Aguirre P, DeLellis RA (1984) Argyrophilia, serotonin, and peptide hormones in the female genital tract and its tumors. Int J Gynecol Pathol 3: 51–70PubMedCrossRefGoogle Scholar
  375. 372.
    Scully RE, Cohen RB (1964) Oxidative-enzyme activity in normal and pathologic human ovaries. Obstet Gynecol 24: 667–681PubMedGoogle Scholar
  376. 373.
    Scully RE, Dickerson GR (1989) Letter to the editor. Int J Gynecol Pathol 8: 196Google Scholar
  377. 374.
    Scully RE, Morris JMcL (1957) Functioning ovarian tumors. In: Meigs J, Sturgis SH (eds) Progress in Gynecology III, Chapter 2. New York, Grune and Stratton, pp 20.Google Scholar
  378. 375.
    Scully RE, Richardson GS (1961) Luteinization of the stroma of metastatic cancer involving the ovary and its endocrine significance. Cancer 14: 827–840PubMedCrossRefGoogle Scholar
  379. 376.
    Senekjian EK, Weiser PA, Talerman A, et al (1989) Vinblastine, cisplatin, cyclophosphamide, bleomycin, doxorubicin, and etoposide in the treatment of small cell carcinoma of the ovary. Cancer 64: 1183–1187PubMedCrossRefGoogle Scholar
  380. 377.
    Serment HL, Laffargue P, Piana L, Blanc B (1970) Ovarian hormone tumors of female children. Int J Gynaecol Obstet 8: 409Google Scholar
  381. 378.
    Serov SF, Scully RE, Sobin LH (1973) International Histological Classification of Tumours, No. 9. Histological Typing of Ovarian Tumours. Geneva, World Health Organization.Google Scholar
  382. 379.
    Shah KH, Steele HD (1981) Sclerosing stromal tumor of the ovary. A case report and further observations. Diagn Gynecol Obstet 3: 155–159PubMedGoogle Scholar
  383. 380.
    Sher J, Marsh M (1963) Multilocular cystic granulosa cell tumor. Am J Clin Pathol 40: 72PubMedGoogle Scholar
  384. 381.
    Shetty MR, Boghossian HM, Duffell D, Freel R, Gonzalez JC (1982) Tumor induced hypoglycemia. A result of ectopic insulin production. Cancer 49: 1920–1923PubMedCrossRefGoogle Scholar
  385. 382.
    Shiel WC, Prete PE, Jason M, Andrews BS (1985) Palmar fasciitis and arthritis with ovarian and non-ovarian carcinomas. New syndrome. Am J Med 79: 640–644PubMedCrossRefGoogle Scholar
  386. 383.
    Siegman-Igra Y, Flatau E, Deligdish L (1977) Chronic diffuse intravascular coagulation (DIC) in nonmetastatic ovarian cancer. Report of a case and review of the literature. Gynecol Oncol 5: 92–100PubMedCrossRefGoogle Scholar
  387. 384.
    Silva PD, Porto M, Moyer DL, Lobo RA (1988) Clinical and ultrastructural findings of an androgenizing Krukenberg tumor in pregnancy. Obstet Gynecol 71: 432–434PubMedGoogle Scholar
  388. 385.
    Silverberg SG (1971) Brenner tumor of the ovary: A clinicopathologic study of 60 tumors in 54 women. Cancer 28: 588–596PubMedCrossRefGoogle Scholar
  389. 386.
    Simmons RL, Sciarra JJ (1967) Treatment of late recurrent granulosa cell tumors of the ovary. Surg Gynecol Obstet 124: 65PubMedGoogle Scholar
  390. 387.
    Sjostedt S, Wahlen T (1961) Prognosis of granulosa cell tumors. Acta Obstet Gynecol Scand 40: 1Google Scholar
  391. 388.
    Smith JP, Rutledge F (1970) Chemotherapy in the treatment of cancer of the ovary. Am J Obstet Gynecol 107: 691PubMedGoogle Scholar
  392. 389.
    Snider BL, Benjamin DR (1981) Eruptive keratoacanthoma with an internal malignant neoplasm. Arch Dermatol 117: 788–790PubMedCrossRefGoogle Scholar
  393. 390.
    Snyder RR, Tavassoli FA (1986) Ovarian strumal carcinoid: Immunohistochemical, ultrastructural, and clinico-pathologic observations. Int J Gynecol Pathol 5: 187–201PubMedCrossRefGoogle Scholar
  394. 391.
    Solh HM, Azoury RS, Najjar SS (1983) Peutz-Jeghers syndrome associated with precocious puberty. J Pediatr 103: 593–595PubMedCrossRefGoogle Scholar
  395. 392.
    Solomon SD, Maurer KH (1983) Association of dermatomyositis and dysgerminoma in a 16-year-old patient. Arthritis Rheum 26: 572–573PubMedCrossRefGoogle Scholar
  396. 393.
    Sotto LSJ, Postoloff AV, Carr F (1956) A case of calcified ovarian fibroma with ossification. Am J Obstet Gynecol 71: 1355PubMedGoogle Scholar
  397. 394.
    Spadoni LR, Lindberg MC, Mottet NK, Herman WL (1965) Virilization coexisting with Krukenberg tumor during pregnancy. Am J Obstet Gynecol 92: 981–991PubMedGoogle Scholar
  398. 395.
    Srivastava KP (1976) Hypoglycemia associated with non-pancreatic mesenchymal tumors. Int Surg 61: 282–286PubMedGoogle Scholar
  399. 396.
    Stagno PA, Petras RE, Hart WR (1987) Strumal carcinoids of the ovary. An immunohistologic and ultrastructural study. Arch Pathol Lab Med 111: 440–446PubMedGoogle Scholar
  400. 397.
    Stenwig JT, Hazekamp JT, Beecham JB (1979) Granulosa cell tumors of the ovary. A clinicopathological study of 118 cases with long-term follow-up. Gynecol Oncol 7: 136PubMedCrossRefGoogle Scholar
  401. 398.
    Sternberg WH (1949) The morphology, endocrine function, hyperplasia and tumors of the human ovarian hilus cells. Am J Pathol 25: 493PubMedGoogle Scholar
  402. 399.
    Sternberg WH, Dhurandhar HN (1977) Functional ovarian tumors of stromal and sex cord origin. Hum Pathol 8: 565PubMedCrossRefGoogle Scholar
  403. 400.
    Sternberg WH, Roth LM (1973) Ovarian stromal tumors containing Leydig cells. 1. Stromal-Leydig cell tumor and non-neoplastic transformation of ovarian stroma to Leydig cells. Cancer 32: 940PubMedCrossRefGoogle Scholar
  404. 401.
    Stewart AF, Romero R, Schwartz PE, Kohorn El, Broadus AE (1982) Hypercalcemia associated with gynecologic malignancies. Biochemical characterization. Cancer 49: 2389–2394PubMedCrossRefGoogle Scholar
  405. 402.
    Stewart KR, Casey MJ, Gondos B (1981) Endodermal sinus tumor of the ovary with virilization. Light and electronmicroscopy study. Am J Surg Pathol 5: 385–391PubMedCrossRefGoogle Scholar
  406. 403.
    Sugiyama M, Kohmoto Y, Miyoshi T, et al (1983) In vivo and vitro steroid biosynthesis by ovarian juvenile granulosa cell tumor of a girl with Olliers disease. Acta Gynaecol Jpn 35: 2185Google Scholar
  407. 404.
    Suit PF, Hart WR (1988) Sclerosing stromal tumor of the ovary. An ultrastructural study and review of the literature to evaluate hormonal function. Cleve Clin J Med 55: 189–194PubMedGoogle Scholar
  408. 405.
    Susil BJ, Sumithran E (1987) Sarcomatous change in granulosa cell tumor. Hum Pathol 18: 397–399PubMedCrossRefGoogle Scholar
  409. 406.
    Swanson PE, Dehner LP (1990) Letter to the Editor. Am J Clin Pathol 94: 805Google Scholar
  410. 407.
    Sweeney EC, Lee G (1979) Granulosa cell tumour of the ovary metastasizing to the heart: A light and electron microscopic study. Ir J Med Sci 148: 11–12CrossRefGoogle Scholar
  411. 408.
    Symonds DA, Driscoll SG (1973) An adrenal cortical rest within the fetal ovary. Report of a case. Am J Clin Pathol 60: 562PubMedGoogle Scholar
  412. 409.
    Synder RR, Tavassoli FA (1986) Ovarian strumal carcinoid. Immunohistochemical, ultrastructural, and clinicopathologic observations. Int J Gynecol Pathol 5: 187–201CrossRefGoogle Scholar
  413. 410.
    Takeda A, Suzumori K, Sugimoto Y, et al (1984) Clear cell carcinoma of the ovary with colony-stimulating-factor production. Occurrence of marked granulocytosis in a patient and nude mice. Cancer 54: 1019–1023PubMedCrossRefGoogle Scholar
  414. 411.
    Takeuchi H, Hamada H, Sodemoto Y, Ushigome S (1983) Juvenile granulosa cell tumor with rapid distant metastases. Acta Pathol Jpn 33: 537PubMedGoogle Scholar
  415. 412.
    Talbott JH (1977) Acute dermatomyositis-polymyositis and malignancy. Semin Arthritis Rheum 6: 305–360PubMedCrossRefGoogle Scholar
  416. 413.
    Talerman A (1987) Ovarian Sertoli-Leydig cell tumor (androblastoma) with retiform pattern: A clinicopathologic study. Cancer 60: 3056–3064PubMedCrossRefGoogle Scholar
  417. 414.
    Talerman A, Haije WG (1985) Letter to the Editor. Int J Gynecol Pathol 4: 171–172PubMedCrossRefGoogle Scholar
  418. 415.
    Talerman A, Hughesdon PE, Anderson MC (1982) Diffuse nonlobular ovarian androblastoma usually associated with feminization. Int J Gynecol Pathol 1: 155–171PubMedCrossRefGoogle Scholar
  419. 416.
    Tamini HK, Bolen J (1984) Enchondromatosis (Ollier’s disease) and ovarian juvenile granulosa cell tumor. Cancer 53: 1605–1608CrossRefGoogle Scholar
  420. 417.
    Tanaka Y, Sasaki Y, Nishihira H, Izawa T, Nishi T (1992) Ovarian juvenile granulosa cell tumor associated with Maffucci’s syndrome. Am J Clin Pathol 97: 523–527PubMedGoogle Scholar
  421. 418.
    Tang M, Liu T (1982) Ovarian sclerosing stromal tumors. Clinicopathologic study of 10 cases. Chinese Med J 95: 186–190Google Scholar
  422. 419.
    Targett CS (1974) Estrogen excretion in a case of theca-granulosa cell tumor. Am J Obstet Gynecol 119: 859PubMedGoogle Scholar
  423. 420.
    Tavassoli FA, Noms HJ (1980) Sertoli tumors of the ovary. A clinicopathologic study of 28 cases with ultrastructural observations. Cancer 46: 2282CrossRefGoogle Scholar
  424. 421.
    Taylor HB, Norris HJ (1967) Lipid cell tumors of the ovary. Cancer 20: 1953PubMedCrossRefGoogle Scholar
  425. 422.
    Teilum G (1958) Classification of testicular and ovarian androblastoma and Sertoli cell tumors. Cancer 11: 769PubMedCrossRefGoogle Scholar
  426. 423.
    Teilum G (1949) Homologous ovarian and testicular tumors. III. Estrogen producing Sertoli cell tumors (androblastoma tubulare lipoides) of the human testis and ovary. J Clin Endocrinol 9: 301CrossRefGoogle Scholar
  427. 424.
    Teilum G (1971) Special Tumors of Ovary and Testis. Comparative Pathology and Histological Identification. Philadelphia, JB Lippincott.Google Scholar
  428. 425.
    Teter J, Bulsld T, Wasilewska B (1962) A virilizing adrenal rest tumor of the ovary with postmenopausal uterine hypertrophy. Bull Pol Med Sci Hist 5: 144Google Scholar
  429. 426.
    Tetu B, Lebel M, Camilleri J (1988) Renin-producing ovarian tumor. A case report with immunohistochemical and electron-microscopic study. Am J Surg Pathol 12: 634–640PubMedGoogle Scholar
  430. 427.
    Tetu B, Ordonez NG, Silva EG (1986) Sertoli-Leydig cell tumor of the ovary with alpha-fetoprotein production. Arch Pathol Lab Med 110: 65–68PubMedGoogle Scholar
  431. 428.
    Tighe JR (1961) Brenner tumours of the ovary: A clinico-pathological study. J Obstet Gynaecol Brit Commonw 68: 292–296CrossRefGoogle Scholar
  432. 429.
    Tiltman AJ (1985) Sclerosing stromal tumor of the ovary: Demonstration of Ligandin in three cases. Int J Gynecol Pathol 4: 362–369PubMedCrossRefGoogle Scholar
  433. 430.
    Todesco S, Terribile V, Borsatti A, et al (1975) Primary aldosteronism due to a malignant ovarian tumor. J Clin Endocrinol Metab 41: 809–819PubMedCrossRefGoogle Scholar
  434. 431.
    Tracy SL, Askin FB, Reddick RL, Jackson B, Kurman RJ (1985) Progesterone secreting Sertoli cell tumor of the ovary. Gynecol Oncol 22: 85–96PubMedCrossRefGoogle Scholar
  435. 432.
    Tsukamoto N, Nakamura M, Ishikawa H (1976) Sclerosing stromal tumor of the ovary. Gynecol Oncol 4: 335–339PubMedCrossRefGoogle Scholar
  436. 433.
    Tyler HR (1974) Paraneoplastic syndromes of nerve, muscle, and neuromuscular junction. Ann NY Acad Sci 230: 348–357PubMedCrossRefGoogle Scholar
  437. 434.
    Tytle T, Rosin D (1984) Bilateral calcified ovarian fibromas. South Med J 77: 1178–1180PubMedCrossRefGoogle Scholar
  438. 435.
    Ueda G, Nobuaki H, Hayakawa K, et al (1972) Clinical histochemical and biochemical studies of an ovarian dysgerminoma with trophoblasts and Leydig cells. Am J Obstet Gynecol 114: 748–754PubMedGoogle Scholar
  439. 436.
    Ueda G, Sato Y, Yamasaki M, et al (1978) Strumal carcinoid of the ovary. Histological, ultrastructural and immunohistological studies with anti-human thyroglobulin. Gynecol Oncol 6: 411–419PubMedCrossRefGoogle Scholar
  440. 437.
    Ulbright TM, Roth LM, Ehrlich CE (1982) Ovarian strumal carcinoid. An immunocytochemical and ultrastructural study of two cases. Am J Clin Path 77: 622–631PubMedGoogle Scholar
  441. 438.
    Ulbright TM, Roth LM, Stehman FB, Talerman A, Senekjian EK (1987) Poorly differentiated (small cell) carcinoma of the ovary in young women: Evidence supporting a germ cell origin. Hum Pathol 18: 175–184PubMedCrossRefGoogle Scholar
  442. 439.
    Vaitukaitis JL (1974) Human chorionic gonadotropin as a tumor marker. Ann Clin Lab Sci 4: 276–280PubMedGoogle Scholar
  443. 440.
    Vassal G, Flamant F, Caillaud JM, et al (1988) Juvenile granulosa cell tumor of the ovary in children: A clinical study of 15 cases. J Clin Oncol 6: 990–995PubMedGoogle Scholar
  444. 441.
    Vaz RM, Turner C (1986) Ollier disease (Enchondromatosis) associated with ovarian juvenile granulosa cell tumor and precocious puberty. J Pediatr 108: 945–947PubMedCrossRefGoogle Scholar
  445. 442.
    Velasco-Oses A, Alonso-Alvaro A, Blanco-Pozo A, et al (1988) Olliers disease associated with ovarian juvenile granulosa cell tumor. Cancer 62: 222–225PubMedCrossRefGoogle Scholar
  446. 443.
    Verducci MA, Malkasian GD, Friedman SJ, Winkelmann RK (1984) Gynecologic carcinoma associated with derma-tomyositis-polymyositis. Obstet Gynecol 64: 695–698PubMedGoogle Scholar
  447. 444.
    Verhoeven ATM, Mastboom JL, Van Leusden HAIM, Van DerVelden WHM (1973) Virilization in pregnancy coexisting with an (ovarian) mucinous cystadenoma: A case report and review of virilizing ovarian tumors in pregnancy. Obstet Gynec Surv 28: 597–622CrossRefGoogle Scholar
  448. 445.
    Vicens E, Martinez-Mora J, Potau N, Sans M, Boix-Ochoa J (1980) Masculinization of a female fetus by Krukenberg tumor during pregnancy. J Pediatr Surg 15: 188–190PubMedCrossRefGoogle Scholar
  449. 446.
    von dem Borne AEGK, van Oers RHJ, Wiersinga WM, et al (1990) Complete remission of autoimmune thrombocytopenia after extirpation of a benign adenofibroma of the ovary. Br J Rheumatol 74: 119–120Google Scholar
  450. 447.
    Waxman M, Damjanov I, Alpert L, Sardinsky T (1981) Composite mucinous ovarian neoplasms associated with Sertoli-Leydig and carcinoid tumors. Cancer 47: 2044PubMedCrossRefGoogle Scholar
  451. 448.
    Waxman M, Vuletin JC, Urcuyo R, Belling CG (1979) Ovarian low-grade stromal sarcoma with thecomatous features. A critical reappraisal of the so-called “malignant thecoma.” Cancer 44: 2206PubMedGoogle Scholar
  452. 449.
    Woodruff JD, Rauh JT, Markley RL (1966) Ovarian Struma. Obstet Gynecol 27: 194–201PubMedGoogle Scholar
  453. 450.
    Woodruff JD, Williams TJ, Goldberg B, Lawterbach M, Preece E (1973) Hormonal activity of the common ovarian neoplasms. Am J Obstet Gynecol 87: 679–695.Google Scholar
  454. 451.
    Yaker A, Benirschke K (1975) A ten year study of ovarian tumors. Virchows Arch A Path Anat Histol 366: 275–286CrossRefGoogle Scholar
  455. 452.
    Yeh E, Meade RC, Ruetz PP (1973) Radionuclide study of struma ovarii. J Nucl Med 14: 118–121PubMedGoogle Scholar
  456. 453.
    Young RH, Dickersin GR, Scully RE (1983) A distinctive ovarian sex cord-stromal tumor causing sexual precocity in the Peutz-Jeghers syndrome. Am J Surg Pathol 7: 223Google Scholar
  457. 454.
    Young RH, Dickersin GR, Scully RE (1984) Juvenile granulosa cell tumor of the ovary. A clinicopathologic analysis of 125 cases. Am J Surg Pathol 8: 575PubMedCrossRefGoogle Scholar
  458. 455.
    Young RH, Dudley AG, Scully RE (1984) Granulosa cell, Sertoli-Leydig cell and unclassified sex cord-stromal tumors associated with pregnancy. A clinicopathological analysis of thirty-six cases. Gynecol Oncol 18: 181PubMedCrossRefGoogle Scholar
  459. 455a.
    Young RH, Oliva E, Scully RE (in press) Lutenized adult granulosa cell tumors of the ovary: A report of four cases. Int J Gynecol Pathol.Google Scholar
  460. 455b.
    Young RH, Oliva E, Scully RE Small cell carcinoma of the ovary, hypercalcemia type. A clinico pathological analysis of 150 cases. Submitted.Google Scholar
  461. 456.
    Young RH, Perez-Atayde AR, Scully RE (1984) Ovarian Sertoli-Leydig cell tumor with retiform and heterologous components. Report of a case with hepatocytic differentiation and elevated serum alpha-fetoprotein. Am J Surg Pathol 8: 709PubMedCrossRefGoogle Scholar
  462. 457.
    Young RH, Prat J, Scully RE (1982) Ovarian endometrioid carcinomas resembling sex cord-stromal tumors. A clinicopathological analysis of 13 cases. Am J Surg Pathol 6: 513–522PubMedCrossRefGoogle Scholar
  463. 458.
    Young RH, Prat J, Scully RE (1982) Ovarian Sertoli-Leydig cell tumors with heterologous elements, (i) Gastrointestinal epithelium and carcinoid: A clinicopathologic analysis of thirty-six cases. Cancer 50: 2448–2456PubMedCrossRefGoogle Scholar
  464. 459.
    Young RH, Prat J, Scully RE (1983) Endometrioid stromal sarcomas of the ovary. A clinicopathological analysis of twenty-three cases. Cancer 53: 1143CrossRefGoogle Scholar
  465. 460.
    Young RH, Scully RE (1991) Malignant melanoma metastatic to the ovary. A clinicopathologic analysis of 20 cases. Am J Surg Pathol 15: 849–860PubMedCrossRefGoogle Scholar
  466. 461.
    Young RH, Scully RE (1992) Ovarian sex cord-stromal tumors. Recent progress. Int J Gynecol Pathol 1: 101CrossRefGoogle Scholar
  467. 462.
    Young RH, Scully RE (1983) Ovarian stromal tumors with minor sex cord elements: A report of seven cases. Int J Gynecol Pathol 2: 227PubMedCrossRefGoogle Scholar
  468. 463.
    Young RH, Scully RE (1983) Ovarian sex cord-stromal tumors with bizarre nuclei. A clinicopathologic analysis of seventeen cases. Int J Gynecol Pathol 1: 325PubMedCrossRefGoogle Scholar
  469. 464.
    Young RH, Scully RE (1983) Ovarian Sertoli-Leydig cell tumors with a retiform pattern: A problem in histopathologic diagnosis. A report of 25 cases. Am J Surg Pathol 77: 755Google Scholar
  470. 465.
    Young RH, Scully RE (1984) Ovarian Sertoli cell tumors. A report of ten cases. Int J Gynecol Pathol 2: 349PubMedCrossRefGoogle Scholar
  471. 466.
    Young RH, Scully RE (1984) Ovarian sex cord-stromal tumors: Recent advances and current status. Clin Obstet Gynecol 11: 93Google Scholar
  472. 467.
    Young RH, Scully RE (1984) Fibromatosis and massive edema of the ovary, possibly related entities. A report of 14 cases of fibromatosis and 11 cases of massive edema. Int J Gynecol Pathol 3: 153PubMedCrossRefGoogle Scholar
  473. 468.
    Young RH, Scully RE (1988) Ovarian sex cord-stromal tumors: Problems in differential diagnosis. Pathol Annu 23(PT I): 237–296.PubMedGoogle Scholar
  474. 469.
    Young RH, Scully RE (1987) Ovarian steroid cell tumors associated with Cushing’s syndrome. A report of three cases. Int J Gynecol Pathol 6: 40–48PubMedCrossRefGoogle Scholar
  475. 470.
    Young RH, Scully RE (1989) Alveolar rhabdomyosarcoma metastatic to the ovary. A report of two cases and discussion of the differential diagnosis of small cell malignant tumors of the ovary. Cancer 64: 899–904PubMedCrossRefGoogle Scholar
  476. 471.
    Young RH, Scully RE (1990) Sarcomas metastatic to the ovary. A report of 21 cases. Int J Gynecol Pathol 9: 231–252PubMedCrossRefGoogle Scholar
  477. 472.
    Young RH, Scully RE (1984) Well-differentiated ovarian Sertoli-Leydig cell tumors. A clinicopathological analysis of 23 cases. Int J Gynecol Pathol 3: 277PubMedCrossRefGoogle Scholar
  478. 473.
    Young RH, Scully RE (1985) Ovarian Sertoli-Leydig cell tumors. A clinicopathological analysis of 207 cases. Am J Surg Pathol 9: 543–569PubMedCrossRefGoogle Scholar
  479. 474.
    Young RH, Welch WR, Dickersin GR, Scully RE (1982) Ovarian sex cord tumor with annular tubules: Review of 74 cases including 27 with Peutz-Jeghers syndrome and 4 with adenoma malignum of the cervix. Cancer 50: 1384PubMedCrossRefGoogle Scholar
  480. 475.
    Yuen BH, Robertson I, Clement PB, Mincey EK (1982) Sclerosing stromal tumor of the ovary. Obstet Gynecol 60: 252–256Google Scholar
  481. 476.
    Zaloudek C, Noms HJ (1982) Granulosa tumors of the ovary in children. A clinical and pathologic study of 32 cases. Am J Surg Pathol 6: 503PubMedCrossRefGoogle Scholar
  482. 477.
    Zaloudek C, Noms HJ (1984) Sertoli-Leydig tumors of the ovary. A clinicopathologic study of 64 intermediate and poorly differentiated neoplasms. Am J Surg Pathol 8: 405–418PubMedCrossRefGoogle Scholar
  483. 478.
    Zaloudek CJ, Tavassoli FA, Noms HJ (1981) Dysgerminoma with syncytiotrophoblastic giant cells. A histologically and clinically distinctive subtype of dysgerminoma. Am J Surg Pathol 5: 361–367PubMedCrossRefGoogle Scholar
  484. 479.
    Zhang J, Young RH, Arseneau J, Scully RE (1982) Ovarian stromal tumors containing lutein or Leydig cells (luteinized thecomas and stromal Leydig cell tumors). A clinicopathological analysis of fifty cases. Int J Gynecol Pathol 1: 270PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Robert H. Young
  • Robert E. Scully

There are no affiliations available

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