Summary of Changes
Melanoma thickness and ulceration, but not level of invasion, are used in the T category (except for Tl melanomas).
The number of metastatic lymph nodes, rather than their gross dimensions and the delineation of clinical occult (i.e., “microscopic”) vs. clinically apparent (i.e., “macroscopic”) nodal metastases, are used in the N category.
The site of distant metastases and the presence of elevated serum lactic dehydrogenase (LDH) are used in the M category.
All patients with Stage I, II, or III disease are upstaged when a primary melanoma is ulcerated.
Satellite metastases around a primary melanoma and in-transit metastases have been merged into a single staging entity that is grouped into Stage IIIc disease.
A new convention for defining clinical and pathologic staging has been developed that takes into account the new staging information gained from intraoperative lymphatic mapping and sentinel node excision.
KeywordsCutaneous Melanoma Primary Melanoma Lymphatic Vessel Invasion Regional Metastasis Desmoplastic Melanoma
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