Non-Monoaminergig Transmitters, Glia Cell Markers, Cell Adhesion Molecules and Synaptic Proteins in Postmortem Brain Tissue
Attempts to transfer findings gained in animal experiments to human depression have raised doubt that altered monoaminergic neurotransmission can fully explain the pathobiology of depression. This review gives a summary of postmortem findings in affective disorders with regard to nonmonoaminergic neurotransmitter systems, glia cell markers, cell adhesion molecules and synaptic proteins. Only relatively few postmortem studies have examined these gene products in affective disorders and a systematic approach together with the application of modern techniques will hopefully reveal unexpected and exiting findings in the near future.
KeywordsBipolar Disorder Frontal Cortex Affective Disorder Vasoactive Intestinal Peptide Synaptic Protein
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