This book represents the exploration of one of medicine’s greatest frontiers — the causes of psychiatric disease. In 1848, when Phineas Gage was injured in a construction accident, it became clear that brain damage could profoundly affect a person’s thinking and behavior. In 1871 Camillo Golgi described neurons, and in 1889 Santiago Ramon y Cajal showed how neurons are linked with each other through axons and dendrites. In 1897 Charles Sherrington described the synapses and chemical transmission the neurons use to communicate. It must have seemed at that time that science was on the threshold of understanding the brain dysfunction that underlies diseases such as schizophrenia, bipolar disorder, and severe depression.
KeywordsBipolar Disorder Severe Depression Psychiatric Disease Peripheral Blood Cell Brain Damage
- Critchley, M. The Divine Banquet of the Brain. Raven Press, New York, NY, 1979; p 267.Google Scholar