Involvement of the Basal Ganglia and Dopamine System in Learning and Execution of Goal-Directed Behavior
To perform any task of our own volition, we execute multiple movements in a specific order based on the likelihood of obtaining a successful outcome. Neurons in the supplementary motor area (SMA), pre-SMA and those in the basal ganglia encode the temporal order, or the sequence of movements used in the tasks (Mushiake and Strick, 1995; Kermadi and Joseph, 1995; Nakamura et al., 1998; Shima and Tanji, 1998, 2000). These neurons must play a crucial role in the mechanisms of planning and execution of temporally organized multiple movements, action.
KeywordsDopamine Catecholamine MPTP Maki Tetrahydropyridine
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