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Nano and Micro Channel Flows of Biomolecular Suspension

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Microfluidics and BioMEMS Applications

Part of the book series: Microsystems ((MICT,volume 10))

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Abstract

In this chapter, we described the two particle methods for simulating flow problems: molecular dynamics (MD) and dissipative particle dynamics (DPD). MD simulates the motion of individual molecules or atoms in a system and provides information on phenomena occurring in atomic scales. DPD is a mesoscaled method dealing with the motion of fluid particles and is feasible to cope with the complex system involving inherently disparate length and time scales, such as polymer suspensions and colloids. The principles, their governing equations and their numerical implementations of these two methods were outlined in this chapter. The molecular models used in polymer rheology were introduced to model biomacromolecules. Some of the simulated results were presented on the flow of a simple liquid through nano periodic nozzles, using MD simulation, and on the flow of a biomacromolecular suspension flow a micro channel, using DPD simulation. Finally, some remarks and findings based on MD and DPD simulations were discussed.

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Authors and Affiliations

  1. Institiute of High Performance Computing, Singapore

    Xijun Fan, Teng Yong Ng, Xuhong Wu & Diao Xu

  2. Bioengineering Division, National University of Singapore, Singapore

    Phan-Thien Nhan

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  1. Xijun Fan
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  2. Phan-Thien Nhan
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  3. Teng Yong Ng
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  4. Xuhong Wu
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  5. Diao Xu
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Editors and Affiliations

  1. The National University of Singapore, Singapore

    Francis E. H. Tay

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© 2002 Springer Science+Business Media Dordrecht

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Fan, X., Nhan, PT., Ng, T.Y., Wu, X., Xu, D. (2002). Nano and Micro Channel Flows of Biomolecular Suspension. In: Tay, F.E.H. (eds) Microfluidics and BioMEMS Applications. Microsystems, vol 10. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-3534-5_8

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  • DOI: https://doi.org/10.1007/978-1-4757-3534-5_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4419-5316-2

  • Online ISBN: 978-1-4757-3534-5

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