Antibodies for Targeted Imaging: Properties and Radiolabeling
Radioimmunodetection has shown great promise as a means of whole-body imaging in patients with various malignant neoplasms. Specificity of the antibody to antigen is a distinguished property of this method. Antibodies used for imaging are being applied for radioimmunotherapy, although effective treatment of solid tumors is still difficult. Recent advances in biotechnology have made possible the production of human antibodies and could prevent immune response. In this chapter, characteristics of antibodies and their fragments and radiolabeling for radioimmunodetection are briefly summarized.
KeywordsTarget Image Beta Emission Murine Antibody Single Photon Emission Compute Tomogra Intact Antibody
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