Imaging of Anticancer Drugs for Therapeutic Response and Prognosis

  • David J. Yang
  • Chun Li
  • E. Edmund Kim


To diagnose cancer, mammography is usually performed in patients with breast cancer; however, the detection rate is low among younger women because of their denser breast tissue. Computed tomography (CT), magnetic resonance imaging (MRI), and ultrasound provide anatomical information but not functional information about cancer. These imaging modalities also are not helpful in assessing or predicting therapeutic response. Thus, to develop an imaging technique to predict the responsiveness of tumors to chemotherapy for individual patients would be most helpful. Drug targeting through a receptor or enzymaticmediated process is an effective way of cellselective drug delivery because this process allows a satisfactory transport rate as well as ligand-dependent cell specificity.


Breast Cancer Standardize Uptake Value None None Tamoxifen Therapy Folate Receptor 


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Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • David J. Yang
  • Chun Li
  • E. Edmund Kim

There are no affiliations available

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