Magnetic Resonance Characteristics of Tumors
Dynamic magnetic resonance imaging (MRI) with rapid sequential image acquisition after bolus injection of gadolinium-diethylene triaminepentaacetic acid (Gd-DTPA) can be used to differentiate benign from malignant lesions. Approximately 84% of malignant tumors exhibited slope values (the slope of the contrastenhancement-over-time curve) higher than 30% per minute; 72% of benign tumors showed slopes lower than 30% per minute . Both benign and malignant tumors showed some overlap resulting in an accuracy of approximately 80 %. The slope values of the time intensity curve of postcontrast dynamic sequences and peak enhancement rates were calculated during the first minute after contrast administration on a pixel-by-pixel basis using a linear fitting algorithm.
KeywordsMagnetization Transfer Ratio Dynamic Magnetic Resonance Imaging Magnetization Transfer Contrast Endorectal Magnetic Resonance Imaging Marked Contrast Enhancement
Unable to display preview. Download preview PDF.
- 4.Erlemann R, Vassallo R, Bongartz G, et al. Musculoskeletal neoplasms: fast low-angle shot MRI with and without Gd-DTPA. Radiology 1990;17: 494–495.Google Scholar
- 16.Cline GW, Magnusson I, Rothman DL, et al. Mechanism of impaired insulin-stimulatedGoogle Scholar
- muscle glucose metabolism in subjects with insulin-dependent diabetes mellitus. J Clin Invest 1997;99:2219–2224.Google Scholar