Abstract
In the previous chapter it was pointed out that biological cells are enclosed by a plasma membrane. This membrane consists of a lipid bilayer and, as seen in Fig. 3.1, the hydrophilic polar heads are oriented facing the intracellular and extracellular water-containing media while the hydrophobic tails, on the other hand, are internal to the membrane. The biophysical consequence of the lipid is a membrane with the high dielectric constant of oil and the high resistivity of that material. We have noted a membrane capacitance of C m = 1 μf/cm2; the lipid membrane specific resistance is 109 Ω cm2.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
B. Hille, Ion Channels of Excitable Membranes, 2nd edn., Sinauer Associates, Sunderland, MA, 1992.
G. Yellen, Ionic permeation and blockade in Ca2+-activated K+ channels in bovine chromaffin cells, J. Gen. Physiol 84:157–186 (1984).
S. Simon, Enter the’ swinging gate,’ Nature 371:103–104 (1994); see also S. L., Slatin, X. Q. Qiu, K. S. Jakes, and A. Finkelstein, Identification of a translocated protein segment in a voltage-dependent channel, Nature 371:158-161 (1994).
R. Kubo, Fluctuation dissipation theorem, Rep. Prog. Phys. London 29:255 (1966).
Books
L. J. De Felice, Introduction to Membrane Noise, Plenum Press, New York, 1981.
L. J. De Felice, Electrical Properties of Cells, Plenum Press, New York, 1997.
B. Sakmann and E. Neher, eds., Single Channel Recording, 2nd edn., Plenum Press, New York, 1995.
H. Lodish, J. E Darnell, and J, Edwin, Molecular Cell Biology, 3rd edn., Scientific American Books, New York, 1995.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2000 Springer Science+Business Media New York
About this chapter
Cite this chapter
Plonsey, R., Barr, R.C. (2000). Channels. In: Bioelectricity. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-3152-1_4
Download citation
DOI: https://doi.org/10.1007/978-1-4757-3152-1_4
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4757-3154-5
Online ISBN: 978-1-4757-3152-1
eBook Packages: Springer Book Archive