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Energy Transfer to Multiple Acceptors, in One, Two, or Three Dimensions

  • Joseph R. Lakowicz

Abstract

In the previous two chapters on energy transfer, we considered primarily covalently linked donor—acceptor pairs, or situations in which there was a single acceptor near each donor. However, there are numerous situations in which there exist multiple acceptors, such as the obvious case of donors and acceptors dissolved in homogeneous solutions. More interesting examples of the multiple-acceptor case occur in membranes and nucleic acids. Suppose that one has a lipid bilayer which contains both donors and acceptors (Figure 15.1, middle). Each donor will be surrounded by acceptors in two dimensions. Since the acceptor distribution is random, each donor sees a different acceptor population. Hence, the intensity decay is an ensemble average and is typically nonexponential. A similar situation exists for donors and acceptors which are intercalated into double-helical DNA (Figure 15.1, right), except that in this case the acceptors are distributed in one dimension along the DNA helix.

Keywords

Energy Transfer Propylene Glycol Transfer Efficiency Malachite Green Close Approach 
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Copyright information

© Springer Science+Business Media New York 1999

Authors and Affiliations

  • Joseph R. Lakowicz
    • 1
  1. 1.University of Maryland School of MedicineBaltimoreUSA

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