A Comparison of Eye Movements in Families with Multiple Occurrence of Schizophrenia and Normal Families

  • Rebekka Lencer
  • Katja Krecker
  • Carsten P. Malchow
  • Achim Nolte
  • Volker Arolt


Why are psychiatrists interested in eye movements? Since the discovery of Diefendorf and Dodge in 1908 and the findings of Holzman and colleagues in 1974 it has been suggested that eye tracking dysfunction (ETD) may serve as a biological marker for schizophrenia in genetic linkage studies (Levinson et al. 1991). Already in those earlier studies a higher prevalence of ETD was found in both schizophrenic patients (50–86%) and their relatives (45%) when compared to normal subjects. ETD as a measurable indicator for vulnerability to schizophrenia may help to identify those individuals who carry the genetic trait without suffering from the disease (Grove et al. 1992).


Schizophrenic Patient Smooth Pursuit Normal Family Phrenic Patient Anticipatory Saccade 
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Copyright information

© Springer Science+Business Media New York 1999

Authors and Affiliations

  • Rebekka Lencer
    • 1
  • Katja Krecker
    • 1
  • Carsten P. Malchow
    • 1
  • Achim Nolte
    • 1
  • Volker Arolt
    • 1
  1. 1.Klinik für PsychiatrieMedizinische Universität zu LübeckLübeckGermany

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