Epstein-Barr Virus Infection and Infectious Mononucleosis

  • James McSherry


First detected in African Burkitt’s lymphoma cells in 1964,1 the Epstein-Barr virus (EBV) was identified as the cause of infectious mononucleosis (IM) in 19682 when a laboratory worker developed antibodies to the virus during an episode of IM. Large-scale seroepidemiologic studies subsequently confirmed the role of EBV in IM. EBV has also been implicated as an etiologic factor in undifferentiated nasopharyngeal carcinoma, B cell lymphomas in immunocompromised individuals, and oral hairy leukoplakia.


Infectious Mononucleosis Cold Agglutinin Slide Test Viral Capsid Antigen Heterophile Antibody 
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© Springer Science+Business Media New York 1998

Authors and Affiliations

  • James McSherry

There are no affiliations available

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