Osteoarthritis (OA) is the most common rheumatic disease affecting humans and the third most common principal diagnosis recorded by family practitioners for office visits made by older patients.1,2 Population-based studies of OA demonstrate that the prevalence of radiographic OA is much higher than is symptomatic OA, and that there is a progressive increase in the prevalence of OA with advancing age.2,3 The prevalence of OA and pattern of joint involvement varies with gender and ethnic and racial background. Knee OA is twice as prevalent in women (18.0%) as men (8.3%) ages 65 through 74.4 Europeans have a higher prevalence of hip OA than do the Chinese and most black populations; U.S. Native Americans have higher rates of OA than U.S. Caucasians; African American women have higher rates of knee OA than Caucasians; and Caucasians have a higher prevalence of polyarticular OA of the hands compared to black Africans and Malaysians.4,5
KeywordsOsteoarthritic Cartilage Crystal Deposition Disease Static Body Position Choline Salicylated Salicylsalicylic Acid
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