Ductal carcinoma in-situ (DCIS), also known as intraductal carcinoma, arises from the ductal epithelium but unlike invasive cancer does not penetrate the basement membrane. Prior to the advent of high quality mammography, patients with DCIS usually presented with palpable masses. Since most of these lesions were large, there was a high incidence of occult invasion and lymph node metastases. With the increased use of screening mammography, the incidence of DCIS has increased dramatically over the last several years, and now most lesions are not palpable. In fact, DCIS currently accounts for up to 45% of all new mammographically detected breast cancers.
KeywordsRadical Mastectomy Atypical Ductal Hyperplasia Screen Mammography Detect Breast Cancer Total Mastectomy
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