Acute Respiratory Distress Syndrome (ARDS) is characterized by 1) hypoxemia (PaO2/FIO2 < 200); 2) bilateral pulmonary infiltrates on CXR; 3) pulmonary capillary wedge pressure (PCWP) < 19, i.e., no clinical evidence of heart failure; 4) acute onset. It is the most severe form of Acute Lung Injury. Causes include infection (>50% of cases), trauma, drugs, pancreatitis, inhalation injury, and aspiration. It has a mortality of approximately 50%, usually due to multiple system organ failure (MSOF), but recovery can be complete.
KeywordsAcute Respiratory Distress Syndrome Pulmonary Capillary Wedge Pressure Inhalation Injury Peak Airway Pressure Multiple System Organ Failure
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