Diverticular disease of the colon is an acquired condition affecting societies that consume a refined, fiber-deficient diet. Consequently, the degree of colonic muscle contraction needed to propel hard, inspissated stools caudally is increased and this, in turn, causes herniation of mu-cosa through weakened points in the bowel wall. Most diverticula are located in the sigmoid colon and do not produce Symptoms. Occasion-ally, a diverticulum will become infected with normal colonic flora as a result of stasis or mucosal abrasion from a fecalith; this sets in motion a cascade of inflammation which may spread either longitudinally within the wall or transmurally into adjacent structures. A patient will then experience left lower quadrant pain. Other conditions which produce a similar clinical picture include Cancer, ischemic Colitis, inflammatory bowel disease, and irritable bowel Syndrome.
KeywordsInflammatory Bowel Disease Irritable Bowel Syndrome Sigmoid Colon Bowel Wall Diverticular Disease
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