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The Effects of Oxidative Stress on the Redox System of the Human Erythrocyte

  • İ. Hamdi Öğüş
  • Mevhibe Balk
  • Yasemin Aksoy
  • Meltem Müftüoğlu
  • Nazmi Özer
Chapter
Part of the NATO ASI Series book series (NSSA, volume 296)

Abstract

Erythrocytes are a group of cells which do not contain a nucleus, mitochondria and other cytoplasmic organelles. Due to the lack of a nucleus and other organelles they can not synthesize proteins and their energy metabolism depends solely on anaerobic glycolysis. The function of these highly differentiated cells is to exchange respiratory gasses between the lung and the tissues. The gas transporting protein, hemoglobin, constitutes 95% of the erythrocyte proteins. Hemoglobin consists of a nonprotein heme group and the protein, globulin. Heme contains iron. For a functional protein this iron must be in the ferrous (Fe2+) state (Mathews and van Holde, 1996; Stryer, 1988).

Keywords

Glutathione Reductase Pentose Phosphate Pathway Human Erythrocyte Redox System Anaerobic Glycolysis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • İ. Hamdi Öğüş
    • 1
  • Mevhibe Balk
    • 1
  • Yasemin Aksoy
    • 1
  • Meltem Müftüoğlu
    • 1
  • Nazmi Özer
    • 1
  1. 1.Department of Biochemistry Faculty of MedicineHacettepe UniversitySihhiye, AnkaraTurkey

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