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Vitamin D pp 239-271 | Cite as

Vitamin D Assays and Their Clinical Utility

  • Ronald L. Horst
  • Bruce W. Hollis
Chapter
Part of the Nutrition and Health book series (NH)

Abstract

More than 70 years ago, vitamin D was demonstrated to be an essential dietary constituent (1). During the ensuing decades, its mode of action and physiologic function have received intense investigation. Research since 1968 has shown that vitamin D undergoes hydroxylations at the C25 (2) and Cl(3–5). This biotransformation to 1,25-dihydroxyvitamin D [1,25(OH)2D] is necessary for the vitamin to become the most potent known stimulator of calcium and phosphorus absorption by the intestinal mucosa and calcium and phosphorus resorption from bone.

Keywords

Radioreceptor Assay Silica Cartridge Antimony Trichloride Borosilicate Glass Tube Glass Culture Tube 
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Copyright information

© Springer Science+Business Media New York 1999

Authors and Affiliations

  • Ronald L. Horst
  • Bruce W. Hollis

There are no affiliations available

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