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Molecular Studies on the Role of Dietary Fat and Cholesterol in Breast Cancer Induction

  • Michael C. Archer
  • Ahmed El-Sohemy
  • Laurie L. Stephen
  • Alaa F. Badawi
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 422)

Abstract

It has been known for many years that rates of breast cancer vary five to ten-fold between countries1. Furthermore, migrants from low to high-risk countries adopt the rates of their new country2. This type of evidence, albeit indirect, strongly suggests that environmental factors play a role in breast cancer development. There is also substantial evidence that genetic and hormonal factors contribute significantly.3,4 Although there are many hypotheses to account for the role of the environment, diet is undoubtedly one of the most important.5 A number of years ago, Doll and Peto estimated that as much as 50% of breast cancer in North America might be prevented by changes in diet.6

Keywords

Breast Cancer Mammary Gland Dietary Cholesterol Breast Cancer Development Mammary Carcinogenesis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • Michael C. Archer
    • 1
  • Ahmed El-Sohemy
    • 1
  • Laurie L. Stephen
    • 1
  • Alaa F. Badawi
    • 1
  1. 1.Department of Nutritional Sciences Faculty of MedicineUniversity of TorontoTorontoCanada

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