Neonatal Screening for Thyroid Disease
Mid-1970 will long be remembered for the final convulsions of the Vietnam war and the lasting effect it has had on society. Yet an equally important event of far reaching social consequence also dates to then. Few are aware that this period marked the turning point in the battle against an insidious crippler of children. The disorder, congenital hypothyroidism, was almost impossible to detect because of the absense of conspicuous clinical features at birth and in the perinatal period. Consequently, by the time the diagnosis was clinically apparent, brain damage had usually ensued leaving in its wake a mentally retarded child and a stricken family. Although treatment with levothyroxine at this juncture resulted in normal growth, intellectual development remained forever compromised.
KeywordsNewborn Screening Congenital Hypothyroidism Neonatal Screening Primary Hypothyroidism Primary Marker
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