Abstract
One of the major factors limiting the development and application of biofunctional membranes is membrane fouling, the irreversible alteration in the membrane caused by specific physical and/or chemical interactions with various components present in the process stream. Fouling can cause dramatic changes in the rate of solute transport through the membrane, potentially destroying the membrane’s ability to function in the particular biomedical device, biosensor, or bioreactor.
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References
A.D. Marshall, P.A. Munro, and G. Tragardh, The effect of protein fouling in microfiltration and ultrafiltration on permeate flux, protein retention and selectivity: a literature review, Desalination 91:65 (1993).
B.C. Robertson and A.L. Zydney, Protein adsorption in asymmetric ultrafiltration membranes with highly constricted pores, J. Colloid Inteiface Sci. 134:563 (1990).
J.M. Sheldon, I.M. Reed, and C.R. Hawes, The fine-structure of ultrafiltration membranes. II. Protein fouled membranes, J. Membrane Sci. 62:87 (1991).
G. Belfort, R.H. Davis, and A.L. Zydney, The behavior of suspensions and macromolecular solutions in crossflow microfiltration, J. Membrane Sci. 96:1 (1994).
W.R. Bowen and D.T. Hughes, Properties of microfiltration membranes. Adsorption of bovine serum albumin at aluminum oxide membranes, J. Membrane Sci. 51:189 (1990).
W.S. Opong and A.L. Zydney, Hydraulic permeability of deposited protein layers formed during ultrafiltration, J. Colloid Interface Sci. 142:41 (1991).
S. Mochizuki and A.L. Zydney, Effect of protein adsorption on the transport characteristics of asymmetric ultrafiltration membranes, Biotech. Prog. 8:553 (1992).
R. Boyd, L.J. Langsdorf, and A.L. Zydney, A two-layer model for the effects of blood contact on membrane transport in artificial organs, Trans. Am. Soc. Artif. Intern. Organs 40:M864 (1994).
L.J. Langsdorf and A.L. Zydney, Effect of blood contact on the transport properties of hemodialysis membranes: a two-layer membrane model, Blood Purification (1995).
S.T. Kelly and A.L. Zydney, Effect of thiol-disulfide interchange reactions on albumin fouling during membrane microfiltration, Biotech. Bioeng. 44:972 (1994).
D.N. Lee and R.L. Merson, Examination of cottage cheese whey by scanning electron microscopy: relationship to membrane fouling during ultrafiltration, J. Dairy Sci. 58:1423 (1974).
S.P. Palecek and A.L. Zydney, Hydraulic permeability of protein deposits formed during microfiltration: effect of solution pH and ionic strength, J. Membrane Sci. 95:71 (1994).
S. Mochizuki and A.L. Zydney, Sieving characteristics of albumin deposits formed during microfiltration, J. Colloid Interface Sci. 159:136 (1993).
S.T. Kelly, W.S. Opong, and A.L. Zydney, The influence of protein aggregates on the fouling of microfiltration membranes during stirred cell filtration, J. Membrane Sci. 80:175 (1993).
S.T. Kelly and A.L. Zydney, Fouling mechanisms during BSA microfiltration, J. Membrane Sci. (1995).
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© 1996 Springer Science+Business Media New York
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Zydney, A.L. (1996). Non-Specific Protein-Membrane Interactions: Adsorption and Fouling. In: Butterfield, D.A. (eds) Biofunctional Membranes. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-2521-6_19
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DOI: https://doi.org/10.1007/978-1-4757-2521-6_19
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4419-3254-9
Online ISBN: 978-1-4757-2521-6
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