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Wilms Tumor-Susceptibility Loci

  • Vicki Huff
Part of the Contemporary Biomedicine book series (CB, volume 12)

Abstract

Nephroblastoma, or Wilms tumor (WT), is a childhood tumor of the kidney that was described and characterized in several case reports and reviews during the 19th century. It acquired its commonly used eponym after Max Wilms published a monograph on the subject in 1899. Occurring with a frequency of roughly 1 in 10,000 live births (Matsunaga, 1981; Breslow et al., 1983), WT is one of the most common solid tumors of children. Fortunately, it is also one of the most successfully treated childhood cancers; with a triple modality therapy of surgery, chemotherapy, and radiotherapy, the overall 2-yr, disease-free survival rate is now 85% (D’Angio et al., 1989).

Keywords

Zinc Finger Domain Maternal Allele Embryonal Tumor Fetal Kidney Beckwith Wiedemann Syndrome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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  • Vicki Huff

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