The Prokaryotes pp 3983-3986 | Cite as

The Genus Leptotrichia

  • Tor Hofstad


The oral cavity of humans is the natural habitat of several different kinds of filamentous organisms, including the Gram-negative anaerobic bacterium Leptotrichia buccalis. This organism, which is the only species of the genus Leptotrichia, was among the first microorganisms to be recognizably described and drawn in the letters of Antoni van Leeuwenhoek.


Oral Cavity Infective Endocarditis Blood Agar Dental Plaque Oral Biol 


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Literature Cited

  1. Baboolal, R. 1968. Identification of filamentous micro-organisms of the human dental plaque by immunofluorescence. Caries Res. 2: 273–280.PubMedCrossRefGoogle Scholar
  2. Bibby, B. G., and G. P. Berry. 1939. A cultural study of filamentous bacteria obtained from the human mouth. J. Bacteriol. 38: 263–274.PubMedPubMedCentralGoogle Scholar
  3. Bee, J. 1941. Fusobacterium: Studies on its bacteriology, serology and pathogenicity. Skr. Norske VidenskapsAkademi. I. Matematisk-naturvitenskapelig klasse No. 9, Oslo, 1941.Google Scholar
  4. Bee, J., and T. S. Thjetta. 1944. The position of Fusobacterium and Leptotrichia in the bacteriological system. Acta Pathol. Microbiol. Scand. 21: 441–450.CrossRefGoogle Scholar
  5. Bollgren, I., G. Källenius, C.-E. Nord, and J. Winberg. 1979. Periurethral anaerobic microflora of healthy girls. J. Clin. Microbiol. 10: 419–424.PubMedPubMedCentralGoogle Scholar
  6. Brown, A. T., and M. L. Gross. 1981. Regulation of lactic acid production by Leptotrichia buccalis. Caries Res. 15: 21–25.PubMedCrossRefGoogle Scholar
  7. Collins, M. D., and C. S. Cummins. 1986. Genus Corynebacterium Lehmann and Neumann 1896, 35o. p. 1266–1283. In P. H. A. Sneath, N. S. Mair, M. E. Sharpe, and J. G. Holt (ed.), Bergey’s manual of systematic bacteriology, vol. 2. Williams and Wilkins, Baltimore.Google Scholar
  8. Davis, G. H. G., and A. C. Baird-Parker. 1959. Leptotrichia buccalis. Br. Dent. J. 106: 70–73.Google Scholar
  9. Duperval, R., S. Béland, and J. A. Marcoux. 1984. Infective endocarditis due to Leptotrichia buccalis: a case report. Can. Med. Assoc. J. 130: 422–425.PubMedPubMedCentralGoogle Scholar
  10. Evaldson, G., G. Carlström, A. Lagrelius, A-S. Malmborg, and C. E. Nord. 1980. Microbiological findings in pregnant women with premature rupture of the membranes. Med. Microbiol. Immunol. 168: 283–297.PubMedCrossRefGoogle Scholar
  11. Falkler, W. A., Jr., and C. E. Hawley. 1976. Antigens of Leptotrichia buccalis. I. Their serologic reaction with human sera. J. Periodont. Res. 10: 211–215.Google Scholar
  12. George, W. L., B. D. Kirby, V. L. Sutter, D. M. Citron, and S. M. Finegold 1981. Gram-negative anaerobic bacilli: Their role in infection and patterns of susceptibility to antimicrobial agents. II. Little-known Fucobacterium species and miscellaneous genera. Rev. Infect. Dis. 3: 599–626.PubMedCrossRefGoogle Scholar
  13. Goldstein, E. J. C., D. M. Citron, B. Wield, U. Blackman, V. L. Sutter, T. A. Miller, and S. M. Finegold 1978. Bacteriology of human and animal bite wounds. J. Clin. Microbiol. 8: 667–672.PubMedPubMedCentralGoogle Scholar
  14. Gustafson, R. L., A. V. Kroeger, J. L. Gustafson, and E. M. K. Vaichulis. 1966. The biological activity of Leptrotrichia buccalis endotoxin. Arch. Oral Biol. 11: 1149–1162.PubMedCrossRefGoogle Scholar
  15. Hamilton, R. D., and S. A. Zahler. 1957. A study of Leptrotrichia buccalis. J. Bacteriol. 73: 386–393.PubMedPubMedCentralGoogle Scholar
  16. Hawley, C. E., and W. A. Falkler, Jr. 1976. Antigens of Leptotrichia buccalis. II. Their reaction with complement fixing IgM in human sera. J. Periodont. Res. 10: 216–223.CrossRefGoogle Scholar
  17. Hillman, J. D., J. Van Houte, and R. J. Gibbons. 1970. Sorption of bacteria to human enamel powder. Arch. Oral Biol. 15: 899–903.PubMedCrossRefGoogle Scholar
  18. Hine, M. K., and G. P. Berry 1937. Morphological and cultural studies of the genus Fusiformis. J. Bacteriol. 34: 517–533.PubMedPubMedCentralGoogle Scholar
  19. Hofstad, T., and K. A. Selvig. 1969. Ultrastructure of Lep- totrichia buccalis. J. Gen. Microbiol. 56: 23–26.PubMedCrossRefGoogle Scholar
  20. Kasai, G. J. 1961. A study of Leptotrichia buccalis. I. Morphology and preliminary observations. J. Dent. Res. 40: 800–811.Google Scholar
  21. Kasai, G. J. 1965. A study of Leptotrichia buccalis. II. Biochemical and physiological observations. J. Dent. Res. 44: 1015–1022.PubMedCrossRefGoogle Scholar
  22. Kligler, I. J. 1915. A biochemical study and differentiation of oral bacteria with special reference to dental caries. J. All. Dent. Soc. 10: 282–330.Google Scholar
  23. Kohler, J. R., D. Raoult, H. Gallais, M. Pons, Y. Peloux, and P. Casanova. 1982. Septicemie a Leptotrichia buccalis chez un immunodeprimé. Pathol. Biol. 30: 161–162.PubMedGoogle Scholar
  24. McCarthy, C., M. L. Snyder, and R. B. Parker. 1965. The indigenous oral flora of man-I. The newborn to the 1year-old infant. Arch. Oral Biol. 10: 61–70.PubMedCrossRefGoogle Scholar
  25. Mergenhagen, S. E., W. C. de Araujo, and E. Varah. 1965. Antibody to Leptotrichia buccalis in human sera. Arch. Oral Biol. 10: 29–33.PubMedCrossRefGoogle Scholar
  26. Miller, W. D. 1889. Die Mikroorganismen der Mundhohle. Die örtlichen und allgemeinen Erkrankungen, welche durch dieselben hervorgerufen werden, p. 50–53. Georg Thieme Verlag, Leipzig.Google Scholar
  27. Morgenstein, A. A., O. M. Citron, and S. M. Finegold. 1981. New medium selective for Fusobacterium species and differential for Fusobacterium necrophorum. J. Clin. Microbiol. 13: 666–669.PubMedPubMedCentralGoogle Scholar
  28. Morgenstein, A. A., D. M. Citron, B. Orisek, and S. M. Finegold. 1986. Serious Infection with Leptotrichia buccalis. Report of a Case and Review of the Literature. Am. J. Med. 69: 782–785.CrossRefGoogle Scholar
  29. Morris, E. O. 1954. The bacteriology of the oral cavity. V. Corynebacterium and Gram-positive filamentous organisms. Br. Dent. J. 97: 29–36.Google Scholar
  30. Prévot, A. R., A. Turpin, and P. Kaiser. 1967. Les bactéries anaérobies. Dunod, Paris.Google Scholar
  31. Reig, M., E Baquero, M. Garcia-Campello, and E. Loza. 1985. Leptotrichia buccalis bacteremia in neutropenic children. J. Clin. Microbiol. 22: 320–321.Google Scholar
  32. Robin, C. 1853. Histoire naturelle de végétaux parasites qui crossent sur l’homme et sur les animaux vivants. J.-B. Baillière, Paris.Google Scholar
  33. Slack, G. L., and G. H. Bowden. 1965. Preliminary studies of experimental plaque in vivo, p. 193–215. In: J. L. Hardwick et al. (ed.), Advances in fluorine research and dental caries prevention, vol. 3. Proc. 11th Congress of the European Organization for Research on Fluorine and Dental Caries Prevention, Sandefjord, Norway 79 July, 1964. Pergamon Press, Oxford.Google Scholar
  34. Spaulding, E. H., and L. F. Rettger. 1937a. The Fusobacterium genus. I. Biochemical and serological classification. J. Bacteriol. 34: 535–548.PubMedPubMedCentralGoogle Scholar
  35. Spaulding, E. H., and L. E Rettger. 1937b. The Fusobacterium genus. II. Some observations on growth requirements and variation. J. Bacteriol. 34: 549–563.PubMedPubMedCentralGoogle Scholar
  36. Sutter, V. L., D. M. Citron, M. A. C. Edelstein, and S. M. Finegold. 1985. Wadsworth anaerobic bacteriology manual, 4th edition. Star Publishing Company, Belmont, CA.Google Scholar
  37. Thadepalli, H., and B. Rao. 1979. Clinical evaluation of mezlocillin. Antimicrob. Ag. Chemoter. 16: 605–610.CrossRefGoogle Scholar
  38. Thjotta, T., O. Hartmann, and J. Brie. 1939. A study of Leptotrichia Trevisan. History, morphology, biological and serological characteristics. Skr. Norske Videnskaps-Akademi. I. Matematisk-naturvitenskapelig klasse No. 5, Oslo.Google Scholar
  39. Trevisan, V. 1879. Prime linee d’introduzione allo studio dei Batter] italiani. Rendiconti dell’istituto lombardo di scienze, Ser. 2 12: 133–151.Google Scholar
  40. Walker, C. B., D. Ratliff, D. Müller, R. Mandell, and S. S. Socransky 1979. Medium for selective isolation of Fusobacterium nucleatum from human periodontal pockets. J. Clin. Microbiol. 10: 844–849.PubMedPubMedCentralGoogle Scholar
  41. Wherry, W. B., and W. W. Oliver. 1916. Leptothrix innominata (Miller). J. Infect. Dis. 19: 299–303.Google Scholar

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© Springer Science+Business Media New York 1992

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  • Tor Hofstad

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