Some Aspects of Omega-3 Fatty Acids from Different Foods

  • Joyce L. Beare-Rogers


The most widely available omega-3 fatty acid in common diets comes from plants. Omega-3 linolenic acid has to be converted to docosahexaenoic acid to exert its essential role as a constituent of neural membranes. This paper will attempt to describe some dietary sources of omega-3 linolenic acid, its likelihood of conversion and an example of metabolic control with linolenic acid contrasted with marine omega-3 fatty acids.


Linolenic Acid Essential Fatty Acid Docosahexaenoic Acid Eicosapentaenoic Acid Domoic Acid 


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  1. Agradi, E., and Galli, C. 1988, Requirement and role of essential fatty acids during brain development. Contr. Infusion Ther. Clin. Nutr., 19: 128.Google Scholar
  2. Brenner, R.R. and Peluffo, R., 1966, Effect of saturated and unsaturated fatty acids on the desaturation in vitro of palmitic, stearic, linoleic and linolenic acids, J. Biol. Chem., 241: 5213.Google Scholar
  3. Budowski, P., 1981, Review: nutritional effects of omega-3 polyunsaturated fatty acids. Isr. J. Med. Sc., 17: 223.Google Scholar
  4. Carlson, S.E., Rhodes, P.G., and Ferguson, M.G., 1986, Docosahexaenoic acid status of preterm infants at birth and following feeding with human milk or formula, Am. J. Clin. Nutr., 44: 798.Google Scholar
  5. Carman, M.A., and Beare-Rogers, J.L., 1988, Influence of diet on (n-3) and (n-6) fatty acids in monkey erythrocytes, Lipids, 23: 501.PubMedCrossRefGoogle Scholar
  6. Crawford, M.A., 1980, Estimation of essential fatty acid requirements in pregnancy and lactation, Prog. Fd. Nutr. Sci., 4: 75.Google Scholar
  7. Crawford, M.A., and Sinclair, A.J., 1972, Nutritional influences in the evolution of mammalian brain, in “Lipids”, pp. 267, Malnutrition and the developing brain, CIBA Foundation Symposium, Amsterdam, Elsevier.Google Scholar
  8. Dyerberg, J., 1986, Linolenate metabolism, reply, Nutr. Res., 44: 316.Google Scholar
  9. Ensinck, J.W., 1988, Dietary omega-3 fatty acid supplementation in type II diabetic:diverse effects on glucose and lipoprotein metabolism. J. Am. Oil Chem., 65: 509.Google Scholar
  10. Hartog, J.M., Lamers, J.M.J., Montfoort, A., Becker, A.E., Klompe, M., Morse, H., ten Cate, F.J., van der Werf, L., Hulsmann, W.C., Hugenholtz, P.G., and Verdouw, P.D., 1987 a, Comparison of mackerel-oil and lard-fat enriched diets on plasma lipids, cardiac membrane phospholipids, cardiovascular performance, and morphology in young pigs, Am. J. Clin. Nutr., 46: 258.Google Scholar
  11. Hartog, J.M., Verdouw, P.D., Klompe,M., and Lamers, Jos, M.J., 1987 b, Dietary mackerel oil in pigs:effect on plasma lipids, cardiac sarcolemmal phospholipids and cardiovascular parameters, J. Nutr., 117: 1371.Google Scholar
  12. Hockstra, W.G., 1975, Biochemical function of selenium and its relation to vitamin E, Fed. Proc., 34: 2083.Google Scholar
  13. Holmer, G., and Beare-Rogers, J.L., 1985, Linseed oil and marine oil as sources of (n-3) fatty acids in rat heart, Nutr. Res., 5: 1011.Google Scholar
  14. Iritani, N., Ikeda, Y., and Kajitani, H., 1984, Selectivities of 1-acylglycerophosphorylcholine acyltransferase and acyl-CoA synthetase for n-3 polyunsaturated fatty acids in platelets and liver microsomes, Biochim. Biophys. Acta, 793: 416.Google Scholar
  15. Leaf, A., and Weber, P.C., 1988, Cardiovascular effects of n-3 fatty acids, New. Eng. J. Med. 318: 549.Google Scholar
  16. Mest, H.J., Bertz, J., Heinroth, I., Blick, H.U., and Forster, W., 1983, The influence of linseed oil diet on fatty acid pattern in phospholipids and thromboxane formation in platelets in man, Klin. Wochenschr., 61: 187.Google Scholar
  17. Mohrhauer, H., and Holman, R.T., 1963, The effect of dose level of essential fatty acids upon fatty acid composition of the rat liver, J. Lipid Res., 4: 151.PubMedGoogle Scholar
  18. Neuringer, M., Connor, W.E., Van Petten, C., and Barstad, L., 1984, Dietary omega-3 fatty acid deficiency and visual loss in infant rhesus monkeys, J. Clin. Invest., 73: 272.Google Scholar
  19. Roshanai, F., and Sanders, T.A.B., 1985, Influence of different supplements of n-3 polyunsaturated fatty acids on blood and tissue lipids in rats receiving high intakes of linoleic acid, Ann. Nutr., 29: 189.Google Scholar
  20. Sanders, T.A.B., and Younger, K.M., 1981, The effect of dietary supplements of omega-3 polyunsaturated fatty acids on the fatty acid composition of platelets and plasma choline phosphoglycerides, Br. J. Nutr., 45: 613.Google Scholar
  21. Sanders, T.A.B., Ellis, F.R., and Dickerson, J.W.T., 1978, Studies of vegans:the fatty acid composition of plasma choline phosphoglycerides, erythrocytes, adipose tissue, and breast milk, and some indicators of susceptibility to ischemic heart disease in vegans and omnivore controls, Am. J. Clin. Nutr., 31: 805.Google Scholar
  22. Tinoco, J., Babcock, R., Hincenbergs, I., Medwadowski, B., Miljanick, P., and Williams, M.A., 1979, Linolenic acid deficiency, Lipids, 14: 166.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • Joyce L. Beare-Rogers
    • 1
  1. 1.Bureau of Nutritional SciencesOttawaCanada

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