Fish (Oil) Consumption and Coronary Heart Disease
The classic epidemiologic studies by Bang and Dyerberg carried out among Greenland Eskimos suggested that a high intake of N-3 polyunsaturated fatty acids through a high intake of marine foods is associated with a low mortality from coronary heart disease (1,2). Also the low mortality from coronary heart disease and the high fish intake in Japan is taken as evidence for the inverse relation between N-3 polyunsaturated fatty acids and coronary heart disease (3). It can, however, not be ruled out that confounding factors may explain the relation between fish intake and coronary heart disease. Therefore epidemiologic studies, both cross-cultural and within populations. are needed in which confounding factors are taken into account. In this paper the relation between fish consumption and coronary heart disease in between and within population studies will be reviewed. Finally recommendations for future research will be given.
KeywordsCoronary Heart Disease Polyunsaturated Fatty Acid Fish Consumption Fish Intake Coronary Heart Disease Mortality
Unable to display preview. Download preview PDF.
- 3.Hirai A., T.Hamazaki, T.Terano, T.Nishikawa, Y. Tamura, A.Kumagai. Eicosapentaenoic acid and platelet function in Japanese. Lancet (1980) 2, 1132Google Scholar
- 8.Keys A., C.Aravanis, H.W.Blackburn, F.S.P.Van Buchem, R.Buzina, B.S. Djordevic, A.S.Dontas, F.Fidanza, M.J.Karvonen, N.Kimura, D.Lekos, M.Monti, V.Puddu, H.L.Taylor. Epidemiological studies related to coronary heart disease: characteristics of men aged 40–59 in seven countries. Acta Med.Scand. (1967) 460, Suppl.1–392Google Scholar
- 9.Keys A.. Coronary heart disease in seven countries. Circulation (1970) 41, Suppl.1–1–211Google Scholar
- 10.Keys A.. Seven countries: A multivariate analysis of death and coronary heart disease. Harvard University Press, Cambridge, Massachusetts (1980)Google Scholar
- 11.Keys A., A.Menotti, M.J.Karvonen, C Aravanis, H.Blackburn, R.Buzina, B.S.Djordevic, A.S.Dontas, F.Fidanza, M.H.Keys, D.Kromhout, S. Nedeljkovic, S.Punsar, F.Seccareccia, H.Toshima. The diet and 15-year death rate in the Seven Countries Study. Am.J.Epidemiol. (1986) 124, 903Google Scholar
- 12.Kromhout D., A.Keys, C.Aravanis, R.Buzina, F.Fidanza, A.Jansen, A.Menotti, S.Nedeljkovic, M.Pekkarinen, B.S. Simic, H.Toshima. Food consumption patterns in the nineteen sixties in seven countries. Am.J.Clin.Nutr. Accepted for publicationGoogle Scholar
- 17.Shekelle R., L.Missell, 0.Paul, A.MacMillan-Schryock, J Stamler. Fish consumption and mortality from coronary heart disease (Letter) N.Eng.J.Med. (1985)313, 820Google Scholar
- 19.Curb J.D., D.M.Reed. Fish consumption and mortality from coronary heart disease (Letter) N.Eng.J.Med. (1985) 313, 821Google Scholar
- 21.Simonsen T., A.Vartun, V.Lyngmo, A.Nordoy. Coronary heart disease, serum lipids, platelets and dietary fish in two communities in Northern Norway. Acta Med.Scand. (1987) 222, 237Google Scholar
- 24.Kromhout D., G.L.Obermann-de Boer, M.B.Katan, L.Havekes, A.Groener, G.Hornstra, E.B.Bosschieter, C.De Lezenne Coulander. The effects of 26 years of habitual fish consumption on serum lipid and lipoprotein levels (The Zutphen Study). Submitted.Google Scholar
- 25.Van Houwelingen R., G.Hornstra, D.Kromhout, C.De Lezenne Coulander. Habitual fish consumption, fatty acids of serum phospholipids and platelet function. Submitted.Google Scholar