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Nephrotoxicity pp 201-206 | Cite as

Silymarin Ameliorates Gentamicin Nephrotoxicity

  • M. K. Chan
  • W. L. Ng

Abstract

Gentamicin (GM) nephrotoxicity is most evident in the proximal tubules which sustain injury as a result of membrane-related events (1–3). Silymarin (SL), an extract from the plant milk thistle, has been shown to exert membrane protective effects (4). The possibility that silymarin may prevent or ameliorate GM-induced nephrotoxicity is investigated in a rat model.

Keywords

Toxicity Peroxide Hepatitis Cage Creatinine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • M. K. Chan
    • 1
  • W. L. Ng
    • 2
  1. 1.Department of MedicineUniversity of Hong KongChina
  2. 2.Department of Pathology, Queen Mary HospitalUniversity of Hong KongHong KongChina

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