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The Effects of Cadmium and Adriamycin on the Isolated Perfused Glomerulus of Myxine Glutinosa (Cyclostomata)

  • L. M. Fels
  • M.-M. Barbey
  • B. Elger
  • J. Abel
  • H. Stolte

Abstract

The severity and mechanisms of action of environmental and drug nephrotoxicity needs to be evaluated. While impaired renal function has often been based on chronic exposure studies, little attention has been paid to acute effects, especially renal dysfunction that occurs shortly after exposure to heavy metals or drugs. It may be difficult to define such changes in the whole animal, but in vitro techniques offer a simpler solution to assessing such changes.

Keywords

Permeability Toxicity Catheter Filtration Albumin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • L. M. Fels
    • 1
    • 3
  • M.-M. Barbey
    • 1
    • 3
  • B. Elger
    • 1
    • 3
  • J. Abel
    • 2
  • H. Stolte
    • 1
    • 3
  1. 1.Division of NephrologyHannover Medical SchoolHannover 61Germany
  2. 2.Medical Institute for Environment HygieneDusseldorfGermany
  3. 3.Mount Desert Island Biological LaboratoryMaineUSA

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