Tubulin as a G-Protein: Regulation of Tubulin-Tubulin Interactions by GTP Hydrolysis

  • Marie-France Carlier
  • Dominique Pantaloni


As proposed by Hughes in 19831, tubulin belongs to, the large family of GTP-binding proteins, which contains several other subclasses: the elongation and initiation factors of protein synthesis, and proteins involved in signal transduction such as G , G., transducin and the Ras p21 proteins ; recently this family has Deen extended to include low molecular weight YPTl and SEC4 proteins involved in the regulation of secretion (for a review see reference 2).


Dynamic Instability Aluminum Fluoride Tubulin Subunit SEC4 Protein Microtubule Dynamic Instability 
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Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • Marie-France Carlier
    • 1
  • Dominique Pantaloni
    • 1
  1. 1.Laboratoire d’EnzymologieCentre National de la Recherche ScientifiqueGif-sur-YvetteFrance

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