Structural and Functional Analysis of ypt Proteins, a Family of ras-Related Nucleotide-Binding Proteins in Eukaryotic Cells
The advance in cloning and sequencing of DNA has led in recent years to the discovery of a large number of genes encoding guanine nucleotide-binding proteins that are related to the potentially oncogenic ras proteins. ras proteins (for review: Barbacid, 1987) and various ras-related proteins are, as far as this has been studied, evolutionary highly conserved. These proteins share similar biochemical properties, they are membrane-bound and likely to be involved in different regulatory pathways in all eukaryotic cells.
KeywordsFission Yeast Membrane Attachment Sec4 Protein Similar Biochemical Property Human Human
Unable to display preview. Download preview PDF.
- Tanabe, T., Nukada, T., Nishikawa, Y., Sugimoto, K., Suzuki, H., and Takahashi, H., Noda, M., Haga, T., Ichiyama, A., Kangawa, K., Minamino, N., Matsuo, H., and Numa, S., 1985, Primary structure of the α-subunit of transducin and its relationship to ras proteins, Nature, 315:242.PubMedCrossRefGoogle Scholar