Prokaryote Molecular Biology
When beginning a study of the genetics of bacteria and bacteriophages, it is important to have clearly in mind the ways in which these prokaryotes and their viruses organize their genetic and molecular processes, and the ways in which these processes differ from those used by eukaryotic organisms. This chapter provides a brief overview of major cell activities with comparisons specifically between the eubacteria, primarily represented by Escherichia coli, and the “lower” eukaryotes, primarily represented by Saccharomyces cerevisiae. The focus in this chapter is on the major molecular biologic processes of DNA replication, transcription, and translation. Specific genetic considerations are the subject of the next chapter. Some of the material in these chapters may be familiar from introductory biology classes, but all of it forms a necessary foundation for the topics to be presented later. The many varied replication and transcription mechanisms found among the bacteria, their plasmids, and their viruses refer back to this material.
KeywordsSigma Factor Replication Fork mRNA Molecule Prokaryotic Cell tRNA Molecule
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