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Epidemiology of Renal Involvement in Diabetes Mellitus

  • Stephen J. Sepe
  • Steven M. Teutsch
Part of the Topics in Renal Medicine book series (TIRM, volume 6)

Abstract

Chronic renal failure ranks as a leading cause of death among people with diabetes mellitus. Prior to clinical onset of diabetic nephropathy, the kidneys of people with diabetes undergo changes in both function and morphology. Functional changes include increases in glomerular filtration rate (GFR) [1] and urinary albumin excretion [2, 3]. The GFR increases by as as much as 20%–30%. Subsequently, intermittent protein excretion occurs and then increases. Ultimately the GFR decreases and end-stage renal disease occurs [4]. Renal failure develops more than 5 years after the onset of constant proteinuria in people with diabetes [5].

Keywords

Diabetic Nephropathy Renal Involvement Diabetic Renal Disease Renal Papillary Necrosis Death Certificate Data 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media Dordrecht 1988

Authors and Affiliations

  • Stephen J. Sepe
  • Steven M. Teutsch

There are no affiliations available

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