Abstract
Ever since the demonstration of high prevalence of hypertension in diabetics by Hitzenberger in 1921 [1], hypertension has been recognized as a major complication of diabetes. However, for a long time, it had remained the Cinderella of diabetology. Only recently, the mechanisms involved in the genesis of hypertension have been studied, its influence on progression of nephropathy has been recognized, and the necessity of rigorous blood pressure control both prior to renal failure and in advanced renal failure has been widely appreciated.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Hitzenberger K: Ãœber den Blutdruck bei Diabetes mellitus. Wien Arch Inn Med 2: 461, 1921.
Hasslacher Ch, Rambausek M, Ritz E: Genesis and management of hypertension of diabetic nephropathy. In: Keen H, Legrain M (eds) prevention and treatment of diabetic nephropathy. MTP Press Limited, 1983, pp 177–189.
Weidmann P: Recent pathogenetic aspects in essential hypertension and hypertension associated with diabetes mellitus. Klin Wochenschr 58: 1071, 1980.
O’Hare JA, Ferriss JB, Brady D, Twomey B, O’Sullivan DJ: Exchangeable sodium and renin in hypertensive diabetic patients with and without nephropathy. Hypertension [Suppl 2] 7: 43–48, 1985.
O’Hare JP, Roland JM, Walters G, Corrall RJM: Impaired sodium excretion in response to volume expansion induced by water immersion in non-insulin-dependent diabetes mellitus. Clin Sci 71: 403–409, 1986.
Sawicki P, Heinemann L, Rave K, Hohmann A, Tilwix F, Berger M: Erhöhte a-ANP Konzentrationen bei Hypertonen Typ-I-Diabetikern, Abhängigkeit vom Grad der Nephropathie. Hochdruck 8:32(a), 1986 [10. Wissenschaftliche Tagung Dtsch. Ges. zur Bekämpfung des Hohen Blutdrucks, Münster, November 1986 ].
De Chatel R, Toth M, Barna I, Büki B, Lang RE: Differential responses in atrial natriuretic peptide and urinary sodium excretion following an intravenous saline load in normal man and in patients with diabetes mellitus. Hochdruck 8:31(a), 1986 [ibid].
Walter-Schräder M-C, Jungmann E, Haak T, Rosak C, Schwab N, Fassbinder W, Althoff PH, Schöffling K: Verminderte natriuretische Wirksamkeit des humanen atrialen natriuretischen Peptides (hANP) bei Patienten mit Typ I Diabetes mellitus. Hochdruck 8:31(a), 1986 [ibid].
Drury PL, Smith GM, Ferriss JB: Increased vascular responsiveness to angiotensin II in type I (insulin-dependent) diabetic patients without complications. Diabetologia 27: 174–179, 1984.
Christlieb AR, Kaldany A, D’Elia JA, Williams GE: Aldosterone responsiveness in patients with diabetes mellitus. Diabetes 27: 732–737, 1978.
Tornita K, Matsuda O, Ideura T, Shiigai T, Takeuchi J: Renin—angiotensin—aldosterone system in mild diabetic nephropathy. Nephron 31: 361–367, 1982.
Wilson TW, Tan LK: Low plasma renin activity in diabetes: relation to urine prostaglandin excretion. Diabetes 34: 145–150, 1985.
Luetscher JA, Kraemer FB, Wilson DM, Schwartz HC, Bryer-Ash M: Increased plasma inactive renin in diabetes mellitus. N Engl J Med 312: 1412–1417, 1985.
Drury PL, Bodansky HJ, Oddie CJ, Cudworth AG, Edwards CRW: Increased plasma renin activity in type 1 diabetes with microvascular disease. Clin Endocrinol 16: 453, 1982.
Ferriss JB, O’Hare JA, Cole M, Kingston SM, Twomey BM, O’Sullivan DJ: Blood pressure in diabetic patients: relationship with exchangeable sodium and renin activity. Diabetic Nephropathy 5: 27–30, 1986.
Walker WG, Hermann J, Murphy R, Patz A: Elevated blood pressure and angiotensin are associated with accelerated loss of renal function in diabetic nephropathy. In: Fourth Int Nutr Metab Renal Disease, Williamsburg, 1985, 80a.
Björck S, Delin K, Herlitz H, Larson O, Aurell M: Renin secretion in advanced diabetic nephropathy. Scand J Urol Nephrol 79: S53, 1984.
Ballermann BJ, Skorecki KL, Brenner BM: Reduced glomerular angiotensin II receptor density in early untreated diabetes mellitus in the rat. Am J Physiol 247: F110 — F116, 1984.
Heidbreder E, Götz R, Schafferhans K, Heidland A: Diminished parathyroid gland responsiveness to hypocalcemia in diabetic patients with uremia. Nephron 42: 285–289, 1986.
Hasslacher Ch, Stech W, Wahl P, Ritz E: Blood pressure and metabolic control as risk factors for nephropathy in type 1 (insulin-dependent) diabetes. Diabetologia 28: 6–11, 1985.
Hasslacher Ch, Ritz E, Terpstra J, Gallasch G, Kunowski G, Rall C: Natural history of nephropathy in type I diabetes: relationship to metabolic control and blood pressure. Hypertension [Supp 2] 7:11–74–11–78, 1985.
Mogensen CE, Christensen CK: Blood pressure changes and renal function in incipient and overt diabetic nephropathy. Hypertension [Suppl 2] 7:11–64–11–73, 1985.
Mauer SM, Steffes MW, Ellen EN, Sutherland DER, Brown DM, Goetz FC: Structural—functional relationships in diabetic nephropathy. J Clin Invest 74: 1143–1155, 1984.
Ritz E, Strumpf C, Katz F, Wing AJ, Quellhorst E: Hypertension and cardiovascular risk factors in hemodialyzed diabetic patients. Hypertension [Suppl 2] 7:11–118—II-124, 1985.
Strumpf C, Katz F, Wing AJ, Ritz E: Cardiovascular risk factors and cardiovascular death in hemodialyzed diabetic patients. Proc Eur Dial Transplant Assoc 21: 202–208, 1984.
Chou LM, Beyer MM, Butt KM, Manis T, Friedman EA: Hypertension jeopardizes diabetic patients following renal transplant. Trans Am Soc Artif Intern Organs 30: 473–478, 1984.
Casale PN, Devereux RB, Milner M, Zullo G, Harshfield GA, Pickering TG, Laragh JH: Value of echocardiographic measurement of left ventricular mass in predicting cardiovascular morbid events in hypertensive men. Ann Intern Med 105: 173–178, 1986.
Munichoodappa D, D’Elia JA, Libertino JA, Gleason RE, Christlieb AR: Renal artery stenosis in hypertensive diabetics. J Urol 121: 555, 1978.
Chihara J, Takebayashi S, Taguchi T, Yokoyama K, Harada T, Naito S: Glomerulonephritis in diabetic patients and its effect on the prognosis. Nephron 43: 45–49, 1986.
Zatz R, Dunn BR, Meyer TW, Anderson S, Rennke HG, Brenner BM: Prevention of diabetic glomerulopathy by pharmacological amelioration of glomerular capillary hypertension. J Clin Invest 77: 1925–1930, 1986.
Anderson S, Meyer TW, Rennke HG, Brenner BM: Control of glomerular hypertension limits glomerular injury in rats with reduced renal mass. J Clin Invest 76: 612–619, 1985.
Ritz E, Hasslacher Ch: Genesis and treatment of hypertension in diabetes mellitus. Diabetic Nephropathy 3: 2, 1984.
Sato T, Nara Y, Note S, Yamori Y: Unproved glucose metabolism in hypertensive diabetic rats by antihypertensive treatment. In: 11th Scient Meet Int Soc Hypert, Heidelberg, August 1986, 0492a.
Topol EJ, Traili TA, Fortuin NJ: Hypertensive hypertrophie cardiomyopathy of the elderly. N Engl J Med 312:277-, 1985.
Massry SG, Feinstein EI, Goldstein DA: Early dialysis in diabetic patients with chronic renal failure. Nephron 23: 2–5, 1979.
Mathiesen ER, Hommel E, Kastrup J, Parving HH: The effect of acute arterial blood pressure reduction on kidney function in incipient and overt diabetic nephropathy. Diabetic Nephropathy 5: 45, 1986.
Cavallo T, Pinto JA, Rajaraman S: Immune complex disease complicating diabetic glomerulosclerosis. Am J Nephrol 4: 347–354, 1984.
Knowler WC, Bennett PH, Ballintine EJ: Increased incidence of retinopathy in diabetics with elevated blood pressure. N Engl J Med 302: 645–650, 1980.
Baldwin DS: Chronic gomerulonephritis: non-immunologic mechanisms of progressive glomerular damage. Kidney Int 21: 109–120, 1982.
Christensen CK, Mogensen CE: Effect of antihypertensive treatment on progression of incipient diabetic nephropathy. Hypertension [Suppl 2] 7:11–109–11–113, 1985.
Christensen CK, Mogensen CE: Long-term antihypertensive treatment reduces both baseline and exercise-induced microalbuminuria in diabetics with incipient nephropathy. Diabetic Nephropathy 5: 46–47, 1986.
Björck S, Nyberg G, Mulec H, Granerus G, Herlitz H, Aurell M: Beneficial effects of angiotensin converting enzyme inhibition on renal function in patients with diabetic nephropathy. Br Med J 293: 471–474, 1986.
Dominguez JR, de la Calle H, Hurtado A, Robles HG, Sancho-Rof J: Effect of captopril on metabolic control in hypertensive patients with type II diabetes. In: Captopril symposium. London: Royal Academy of Physicians, 1985, 25a.
Elling H, Elling H: Penicillamine, captropril and hypoglycemia. Ann Intern Med 103: 644, 1985.
Helgeland A, Hagelund CH, Strommen R, Tretli S: Enalapril, atenolol, and hydrochlorothiazide in mild to moderate hypertension. Lancet 1: 872–875, 1984.
Rett K, Jauch W, Wicklemeyer M, Dietze G, Mehnert H: Experimental and human experienced with ACE inhibition in diabetes: evidence for improvement in glucose metabolism. In: Captopril symposium. London: Royal Academy of Physicians, 1985, 23a.
Taguma Y, Kitamoto Y, Futaki G, Ueda H, Monma H, Ishiziaki M, Takahashi H, Sekino H, Sasaki Y: Effect of captopril on heavy proteinuria in azotemic diabetics. N Engl J Med 313: 1617–1620, 1985.
Malaisse-Lagae F, Mathias PC, Malaisse WJ: Gatting and blocking of calcium channels by dishydropyridines in the pancreatic B-cell. Biochem Biophys Res Commun 123: 1062, 1984.
Bhatnagar SK, Amin MM, Al-Yusuf AR: Diabetogenic effects of nifedipine. Br Med J 289: 19, 1984.
Abadie E, Villette JM, Gauveille C, Tabuteau F, Fiet J: Influence of nifedipine on carbohydrate metabolism in non-insulin-dependent diabetic patients. Diabete Metab 11: 141, 1985.
Trost BN, Weidmann P: Effects of nitrendipine and other calcium antagonists on glucose metabolism in man. J Cardiovasc Pharmacol [Suppl 7] 6: 986, 1984.
Roejdmark S, Andersson DE: Influence of verapamil on glucose tolerance. Acta Med Scand [Suppl 681] 215: 37, 1984.
Hiedland A, Heidbreder E, Hörl WH, Schäfer R: Calcium antagonists in the treatment of hypertension. Contrib Nephrol 33: 254–269, 1982.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1988 Springer Science+Business Media Dordrecht
About this chapter
Cite this chapter
Ritz, E., Hasslacher, C., Mann, J. (1988). Hypertension in Diabetics with Renal Disease. In: Mogensen, C.E. (eds) The Kidney and Hypertension in Diabetes Mellitus. Topics in Renal Medicine, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-1974-1_22
Download citation
DOI: https://doi.org/10.1007/978-1-4757-1974-1_22
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4757-1976-5
Online ISBN: 978-1-4757-1974-1
eBook Packages: Springer Book Archive