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Mechanism of Concentration and Dilution of Urine

  • Esmail Koushanpour
  • Wilhelm Kriz
Chapter

Abstract

In Chapter 9, while discussing the sequential processing of the filtrate along Henle’s loop, we alluded to the role of this nephron segment in concentrating and diluting the urine. In this chapter we consider the principle of countercurrent multiplication and the evidence for its application to the kidney. We then examine the mechanism of concentration and dilution of urine, the measurement of the ability of the kidney to concentrate urine, and finally the action of some selective diuretics and their potential therapeutic effects. We begin with a comprehensive presentation of the structural organization of the renal medulla.

Keywords

Renal Medulla Outer Medulla Collect Duct Tubular Fluid Outer Stripe 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Esmail Koushanpour
    • 1
  • Wilhelm Kriz
    • 2
  1. 1.Northwestern University Medical SchoolChicagoUSA
  2. 2.University of HeidelbergHeidelbergFederal Republic of Germany

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