Vitreous Degeneration in Myopia and Retinitis Pigmentosa
Myopia is the most common ocular disorder diagnosed and managed by the ophthalmologist; retinitis pigmentosa (RP) is seen infrequently. Why consider them together? In many cases both can be shown to have a hereditary basis. This suggests a fundamental metabolic abnormality, that they are “molecular” diseases. Each presents a wide spectrum of severity. Advanced forms of both show decreased retinal function, and both are characterized by premature cataract formation and vitreous degeneration. In a review of similarities and differences, certain notions arise that suggest explanations for clinical observations and present questions for future research.
KeywordsRetinal Pigment Epithelium Retinal Detachment Retinitis Pigmentosa Macular Hole Proliferative Diabetic Retinopathy
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- (1).SCARPA, A. — A treatise on the principal diseases of the eye. 2nd ed., J. Briggs (trans.). London: Cadill Davies, 1818, 392.Google Scholar
- (2).ELSCHNIG, A. — Über Glaskörperablösung. Klin. Monatsbl. Augenheilkd., 1904, 42, 529–538.Google Scholar
- (4).TOLENTINO, F.I., SCHEPENS, C. L., FREEMAN, H. M. — Vitreoretinal disorders: diagnosis and management. Philadelphia: W.B. Saunders, 1976, 284–287.Google Scholar
- (8).SZAMIER, R.B. — Ultrastructure of the preretinal membrane in retinitis pigmentosa. Invest. OphthalmoL Vis. Sci., 1981, 21, 227–236.Google Scholar
- (15).EDWARDS, R.B. — Glycosaminoglycan secretion by primary cultures and subcultures of human retinal pigment epithelium. Birth Defects,1982, 18(6),95–100.Google Scholar
- (17).KLÖTI, R. — Experimental occlusion of retinal and ciliary vessels in owl monkeys. I. Technique and clinical observations of selective embolism of the central retinal artery system. Exp. Eye Res., 1967, 6, 393–399.Google Scholar