Quantitative Assessment of Infarct Size and its Influence by Thrombolysis
Conventional nuclear cardiology employs gamma-emitting tracers such as technetium-99 (99mTc) or thallium-201 (20lT1). Such tracers are not physiological metabolites and accordingly behave somewhat differently from the physiological constituents being traced. Single-photon emitters decay by liberating energy in the form of photons characteristic of the parent radio-nuclide, much of which is absorbed (attenuated) before it reaches the detector. Because of the variability of attenuation it is difficult, if not impossible, to accurately define both the amount of radiation emitted and its location. Thus, even though the reconstructed images may be aesthetically satisfying, quantitative limitations preclude definitive correspondence between the reconstructed image and the actual distribution of tracer in the organ of interest in absolute terms.1
KeywordsPositron Emission Tomography Infarct Size Myocardial Metabolism Tomographic Study Ischemic Zone
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