Abstract
This presentation aims to review the key data sets on the role of elevated serum cholesterol and elevated blood pressure in the production of mass premature coronary heart disease (CHD). Its purpose is to set down the information needed by the health professions and the general public to act effectively in the growing effort to control the contemporary CHD epidemic in the industrialized countries and to prevent its emergence in the developing countries. To aid in accomplishing this objective, a most useful document is the just published report of the World Health Organization Expert Committee on the Prevention of Coronary Heart Disease1This document summarizes current knowledge on these matters and on that basis presents an effective strategy for the health services and the general public for the effort to control this epidemic. (For an extensive review of the research literature in this field — i.e., the scientific basis of the preventive effort — see also the recently published Volume 2 of the Report of the Working Group on Arteriosclerosis of the U.S. National Heart, Lung, and Blood Institute2.
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References
WHO Expert Committee on the Prevention of Coronary Heart Disease. Prevention of Coronary Heart Disease — Report of a WHO Expert Committee, World Health Organization, Geneva, Switzerland, Technical Report Series 678 (1982).
Working Group on Arteriosclerosis of the National Heart, Lung, and Blood Institute, Report of the Working Group on Arteriosclerosis of the National Heart, Lung, and Blood Institute, Vol.2, U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, NIH Publication No. 81–2035, Bethesda, MD, September 1981.
Inter-Society Commission for Heart Disease Resources. Atherosclerosis Study Group and Epidemiology Study Group. Primary Prevention of the Atherosclerotic Diseases, Circulation, 42:A55-A95 (1970). Revised April 1972.
H. Blackburn, J. Chapman, T. R. Dawber, J. T. Doyle, F. H. Epstein, W. B. Kannel, A. Keys, F. Moore, O. Paul, J. Stamler, and H. L. Taylor, Revised Data for 1970 ICHD Report, Letter to the Editor, Amer.Heart J., 94:539–540 (1977).
WHO International Collaborative Group, WHO Regional Office for Europe, Myocardial Infarction Community Registers, Regional Office for Europe, World Health Organization, Copenhagen, Denmark (1977).
E. H. Ackerknecht, “Rudolf Virchow — Doctor, Statesman, Anthropologist,” Madison, WI, University of Wisconsin Press (1953).
A. Keys, ed., “Seven Countries — A Multivariate Analysis of Death and Coronary Heart Disease,” Cambridge, MA, Harvard University Press (1980).
Pooling Project Research Group: Relationship of blood pressure, serum cholesterol, smoking habit, relative weight and ECG abnormalities to incidence of major coronary events: Final report of the Pooling Project, J.Chron.Dis., 31:201–306 (1978).
J. Stamler, Improved life styles: Their potential for the primary prevention of atherosclerosis and hypertension in childhood; the fat-modified diet: its nature, effectiveness, and safety; can an effective fat-modified diet be safely recommended after weaning for infants and children in general? “Childhood Prevention of Atherosclerosis and Hypertension,” Edited by R. M. Lauer and R. B. Shekelle, New York, Raven Press, pp 3–36, 387–403 and 407–410 (1980).
R. B. Shekelle, A. M. Shryock, O. Paul, M. Lepper, J. Stamler, S. Liu, and W. J. Raynor, Jr., Diet, serum cholesterol, and death from coronary heart disease — the Western Electric Study, N.Engl.J.Med., 304:65–70 (1981).
B. Lewis, M. Katan, I. Merkx, N. E. Miller, F. Hammett, R. M. Kay, A. Nobels, and A. V. Swan, Towards an improved lipid-lowering diet: additive effects of changes in nutrient intake, Lancet, 2:1310–1313 (1981).
F. M. Sacks, W. P. Castelli, A. Donner, and E. H. Kass, Plasma lipids and lipoproteins in vegetarians and controls, N.Engl. J.Med., 292:1148–1151 (1975).
F. W. Ashley and W. B. Kannel, Relation of weight change to changes in atherogenic traits: The Framingham Study, J.Chron.Dis., 27:103–114 (1974).
A. W. Caggiula, G. Christakis, M. Farrand, S. B. Hulley, R. Johnson, N. Lasser, J. Stamler, and G. Widdowson, The Multiple Risk Factor Intervention Trial (MRFIT), IV. Intervention on blood lipids, Prev.Med., 10:443–475 (1981).
N. Anitschkow, Experimental arteriosclerosis in animals, “Arteriosclerosis,” Edited by E. V. Cowdry, New York, Macmillan, pp 271–322 (1933).
M. L. Armstrong, E. D. Warner, and W. E. Connor, Regression of coronary atheromatosis in rhesus monkeys, Circ.Res., 27: 59–67 (1970).
T. B. Clarkson, M. G. Bond, B. C. Bullock, and C.A. Marzetta, A study of atherosclerosis regression in macaca mulatta. IV. Changes in coronary arteries from animals with atherosclerosis induced for 19 months and then regressed for 24 or 48 months at plasma cholesterol concentrations of 300 or 200 mg/dl, Exper.Molecular Path., 34:345–368 (1981).
S. Dayton, M. L. Pearce, S. Hashimoto, W. J. Dixon, and U. Tomiyasu, A controlled clinical trial of a diet high in unsaturated fat — In preventing complications of atherosclerosis, Circulation, 39,40 (Suppl.2): 1–63 (1969).
I. Hjermann, I. Holme, K. V. Byre, and P. Leren, Effect of diet and smoking intervention on the incidence of coronary heart disease, Report from the Oslo study group of a randomized trial in healthy men, Lancet, 2:1303–1310 (1981).
R. Stander, J. Stamler, W. F. Riedlinger, G. Algera, and R. H. Roberts, Weight and blood pressure, Findings in hypertension screening of 1 million Americans, JAMA, 240:1607–1610 (1978).
R. Stamler, J. Stamler, W. F. Riedlinger, G. Algera, and R. H. Roberts, Family (Parental) history and prevalence of hypertension: results in a nationwide screening program, JAMA, 241:43–46 (1979).
L. K. Dahl, and R. A. Love, Evidence for relationship between sodium (chloride) intake and human essential hypertension, Arch.Intern.Med., 94:525–531 (1954).
J. Stamler, Hypertension: aspects of risk, J. C. Hunt, T. Cooper, E. D. Frohlich, R. W. Gifford Jr., N. M. Kaplan, J. H. Laragh, H. M. Maxwell, and C. G. Strong, eds., Hypertension Update: Mechanisms, Epidemiology, Evaluation, Management, Health Learning Systems, Inc., Bloomfield, N.J. pp.23–37 (1979).
A. R. Dyer, J. Stamler, O. Paul, D. M. Berkson, R. B. Shekelle, M. H. Lepper, H. McKean, H. A. Lindberg, D. Garside, and T. Tokich, Alcohol, cardiovascular risk factors and mortality: the Chicago experience, Circulation, 64(Suppl.III):III-20-III-27 (1981).
J. Stamler, E. Farinaro, L. M. Mojonnier, Y. Hall, D. Moss, and R. Stamler, Prevention and control of hypertension by nutritional-hygienic means — long-term experience of the Chicago Coronary Prevention Evaluation Program, JAMA, 243:1819–1823 (1980).
Hypertension Detection and Follow-Up Program Cooperative Group, Five-year findings of the Hypertension Detection and Follow-Up Program. I. Reduction in mortality of persons with high blood pressure, including mild hypertension, JAMA, 242: 2562–2571 (1979).
Hypertension Detection and Follow-Up Program Cooperative Group, Five-year findings of the Hypertension Detection and Follow-Up Program. II. Mortality by race-sex and age, JAMA, 242: 2572–2577 (1979).
Hypertension Detection and Follow-Up Program Cooperative Group, Five-year findings of the Hypertension Detection and Follow-Up Program. III. Reduction in stroke incidence among persons with high blood pressure, JAMA, 247:633–638 (1982).
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Stamler, J. (1984). High Blood Cholesterol and High Blood Pressure: State of Knowledge Today and Implications for Prevention and Control of Epidemic Adult Cardiovascular Disease. In: Chazov, E.I., Smirnov, V.N., Oganov, R.G. (eds) Cardiology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-1824-9_13
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DOI: https://doi.org/10.1007/978-1-4757-1824-9_13
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